Microbiology: An Introduction
Microbiology: An Introduction
11th Edition
ISBN: 9780321733603
Author: Gerard J. Tortora, Berdell R. Funke, Christine L. Case
Publisher: Benjamin Cummings
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Chapter 4, Problem 8R

Starch is readily metabolized by many cells, but a starch molecule is too large to cross the plasma membrane. How does a cell obtain the glucose molecules from a starch polymer? How does the cell transport these glucose molecules across the plasma membrane?

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Ammonia (NH3) is a weak base that under acidic conditions becomes protonated to the ammonium ion in the  following reaction: NH3   +  H+   →   NH+4 NH3 freely permeates biological membranes, including those of lysosomes. The lysosome is a subcellular organelle with a pH of about 4.5–5.0; the pH of cytoplasm is about 7.0. What is the effect on the pH of the fluid content of lyso- somes when cells are exposed to ammonia? Note: Ammo- nium (NH4+) does not diffuse freely across membranes.
Draw and label a cell lipid bilayer and diagram how the following transport processes take place: passive diffusion of oxygen into the cell, facilitated diffusion of potassium into the cell, active transport of sucrose into the cell. Using different symbols (circles for oxygen, squares for sucrose, and triangles for potassium ions), show the relative concentrations (gradients) of these substances on the inside and outside of the cell. For example, to show that oxygen enters the cell by going “down” its gradient, you would draw more circles on the outside of the cell than inside the cell. Be sure to show and label membrane proteins when appropriate, and show the electric membrane potential using “+”s (pluses) on one side and “-”s (minuses) on the other side of the membrane. Also show the proton pump which uses ATP as a source of energy.
While endocytosis and exocytosis refer to the direction in which a vesicle moves into and out of a cell respectively, it is important to think about what is being moved with and within the vesicles. To demonstrate how this process is utilized in human cells we will focus on the human body's insulin response. The purpose of the insulin response is to create a pathway for glucose entry into cells by releasing glucose transporters into the membrane. Cell Type #1- insulin producers: In humans, pancreatic B-cells create steroid insulin that can be packaged into vesicles starting at the ER. These vesicles are prepared for exocytosis so that the insulin can be released from the pancreatic B - cells and get into the bloodstream when signaled to do so. When glucose is present in the blood stream these cells will release the pre-packed insulin into the blood stream. Cell Type #2- insulin responders: Other cells do not produce insulin but instead respond when they have received the insulin signal…

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Microbiology: An Introduction

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