Pearson eText for Biochemistry: Concepts and Connections -- Instant Access (Pearson+)
Pearson eText for Biochemistry: Concepts and Connections -- Instant Access (Pearson+)
2nd Edition
ISBN: 9780137533114
Author: Dean Appling, Spencer Anthony-Cahill
Publisher: PEARSON+
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Chapter 4, Problem 1P
Interpretation Introduction

Interpretation:

The following blanks should be filled with suitable substances as mentioned below:

    ……….. Adenosine …….. Uridine
    ……….. Cytidine 5'-monophospahe …….. Deoxycytidine 5'triphosphate
    ……….. Guanine ……… Deoxyuridine
    ……….. Thymine ………. Guanosine 5'-diphosphate
    ……….. Deoxyguanosine ………. Thymidine triphosphate
  1. A nucleobase
  2. A ribonucleoside
  3. A ribonucleotide
  4. A deoxyribonucleoside
  5. A deoxyribonucleotide
  6. A dinucleotide

Concept Introduction:

A nucleobase is a biological compound. It is basically as nitrogen containing base. They form nucleosides and nucleotides which are made up of nucleic acid. The only difference between a nucleoside and nucleotide is presence of phosphate group in the nucleotides. The common between them is a nitrogenous base and a five-carbon sugar. If a nucleoside contain ribose as a component then it is known as ribonucleoside, where ribose is carbohydrate (pentose monosaccharide) with molecular formula C5H10O5. Similarly, ribonucleoside is ribose containing nucleotide. In ribose, if a hydroxyl group is replaced by hydrogen, it become deoxyribose. Thus, deoxyribonucleoside and deoxyribonucleotide are nucleoside and nucleotide with deoxyribose as a component. If there are two units of each of the nitrogenous base, sugar and phosphate group present in a compound it is known as dinucleotide.

Answer:

    (b) A ribonucleoside-Adenosine (b) A ribonucleoside -Uridine
    (c) A ribonucleotide-Cytidine 5'-monophosphate

    (e) A deoxyribonucleotide-

    Deoxycytidine 5'triphosphate

    (a) A nucleobase-Guanine (d) A deoxyribonucleoside-Deoxyuridine
    (a) A nucleobase-Thymine (c) A ribonucleotide- Guanosine 5'-diphosphate
    (d) A deoxyribonucleoside-Deoxyguanosine (e) A deoxyribonucleotide-Thymidine triphosphate

Expert Solution & Answer
Check Mark

Explanation of Solution

The structure of Adenosine and uridine are as follows:

Pearson eText for Biochemistry: Concepts and Connections -- Instant Access (Pearson+), Chapter 4, Problem 1P , additional homework tip  1Pearson eText for Biochemistry: Concepts and Connections -- Instant Access (Pearson+), Chapter 4, Problem 1P , additional homework tip  2

Adenosine Uridine

Both are ribonucleoside as they contain ribofuranose attached by glycosidic bond to the purine nucleoside.

The structure of Cytidine 5'-monophosphate and guanosine 5'-diphosphate are as follows:

Pearson eText for Biochemistry: Concepts and Connections -- Instant Access (Pearson+), Chapter 4, Problem 1P , additional homework tip  3Pearson eText for Biochemistry: Concepts and Connections -- Instant Access (Pearson+), Chapter 4, Problem 1P , additional homework tip  4

Cytidine 5'-monophosphate Guanosine 5'-diphosphate

The nucleoside cytidine and guanine are attached to phosphoric acid through ester linkage, thus, they form a nucleotide. There is also a pentose sugar ribose hence, they are classified as a ribonucleotide. There is one phosphate group in cytidine 5'-monophosphate and two phosphate groups in guanosine 5'-diphosphate.

Guanine and thiamine both are nucleobase, as they are nitrogen containing bases. They are found in nucleic acids DNA and RNA.

The structures are as follows:

Pearson eText for Biochemistry: Concepts and Connections -- Instant Access (Pearson+), Chapter 4, Problem 1P , additional homework tip  5Pearson eText for Biochemistry: Concepts and Connections -- Instant Access (Pearson+), Chapter 4, Problem 1P , additional homework tip  6

Guanine Thymine

Deoxyguanosine and deoxyuridine are deoxyribonucleoside as they contain deoxyribose without phosphate group.

The structures are as follows:

Pearson eText for Biochemistry: Concepts and Connections -- Instant Access (Pearson+), Chapter 4, Problem 1P , additional homework tip  7Pearson eText for Biochemistry: Concepts and Connections -- Instant Access (Pearson+), Chapter 4, Problem 1P , additional homework tip  8

Deoxyguanosine Deoxyuridine

Deoxycytidine 5'triphosphate and thymidine triphosphate are deoxyribonucleotide as they contain deoxyribose with phosphate group attached to nucleoside.

The structures are as follows:

Pearson eText for Biochemistry: Concepts and Connections -- Instant Access (Pearson+), Chapter 4, Problem 1P , additional homework tip  9Pearson eText for Biochemistry: Concepts and Connections -- Instant Access (Pearson+), Chapter 4, Problem 1P , additional homework tip  10

Deoxycytidine 5'triphosphate Thymidine triphosphate

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