Biology: How Life Works - Standalone book
Biology: How Life Works - Standalone book
2nd Edition
ISBN: 9781464126093
Author: James Morris, Daniel Hartl, Andrew Knoll, Robert Lue, Melissa Michael, Andrew Berry, Andrew Biewener, Brian Farrell, N. Michele Holbrook
Publisher: W. H. Freeman
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Chapter 37, Problem 6SA
Summary Introduction

To compare:

The force produced by a muscle over time when it is stimulated by a single twitch stimulus with the force produced by multiple stimuli at low frequency, and then with the force produced when the stimulation frequency is increased.

Concept introduction:

The muscle fiber responds to the stimulus provided by the motor neuron by the secretion of the neurotransmitters. The muscle contracts by receiving the electrical impulse. The time duration may vary for each muscle fiber for the contraction and relaxation period.

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You will be building a double-stranded DNA molecule, representing a short (20 base) sequence that could be found in a chromosome.  It will have a 3' --> 5' strand and a 5' --> 3' strand. Use two full 12-base-pair DNA models.  a) Upload a photo of a model once the first 6 nucleotides have been inserted to base pair with the two parent strands. b)Upload a photo of DNA polymerase I and Ligase in "action" removing the RNA primer nucleotides and making new phosphodiester bonds. c)Upload a photo of the final two DNA strands, after Termination, identifying the parent and daughter strands of each.
Write down the 12 base-pairs (ex A-T or G-C) contained in the two models you will us from top to bottom below Model 1 bp:   Model 2 bp:
a) What type of bond does helicase break? b) Which of these two types of bonds is stronger? c) Describe why it is necessary for the lagging strand to be made in fragments, called Okazaki fragments.
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