Prescott's Microbiology
Prescott's Microbiology
10th Edition
ISBN: 9781259281594
Author: Joanne Willey, Linda Sherwood Adjunt Professor Lecturer, Christopher J. Woolverton Professor
Publisher: McGraw-Hill Education
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Chapter 32.3, Problem 1.4RIA
Summary Introduction

To determine:  The physiological role of P.acnes in the establishment of acne vulgaris.

Introduction: Human body is the host of billions of bacteria or microbes. They are considered as normal microbiota or microflora of the human body. These organisms establish a mutualistic relationship with the human body. They are important for the normal functioning of the human body, but the skin does not favor the growth of microbes.

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Plekhg5 functions in bottle cell formation, and Shroom3 functions in neural plate closure, yet the phenotype of injecting mRNA of each into the animal pole of a fertilized egg is very similar. What is the phenotype, and why is the phenotype so similar? Is the phenotype going to be that there is a disruption of the formation of the neural tube for both of these because bottle cell formation is necessary for the neural plate to fold in forming the neural tube and Shroom3 is further needed to close the neural plate? So since both Plekhg5 and Shroom3 are used in forming the neural tube, injecting the mRNA will just lead to neural tube deformity?

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Prescott's Microbiology

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