Chapter 3, Problem 11P

A.

Summary Introduction

To explain: Whether the data is consistent with the hypothesis that titin’s spring like behavior is due to the sequential unfolding of individual Ig domains.

Introduction: Protein is a biomolecule. It consists of a chain of amino acids called polypeptide. Titin is a known largest polypeptide. This molecule extends from thick filament of muscle to the Z disc. This acts as spring to keep the thick filament at the center of the sarcomere. Titin is made up of 89 amino acids,. The polypeptide has repeated immunoglobulin sequences.

B.

Summary Introduction

To explain: The putative magnitude in un-folding domain.

Introduction: Protein is a biomolecule. It consists of a chain of amino acids called polypeptide. Titin is a known largest polypeptide. This molecule extends from thick filament of muscle to the Z disc. This acts as spring to keep the thick filament at the center of the sarcomere. Titin is made up of 89 amino acids,. The polypeptide has repeated immunoglobulin sequences.

C.

Summary Introduction

To explain: The reason that the each successive peak in Fig. Q3-2B a little higher than the one before.

Introduction: Protein is a biomolecule. It consists of a chain of amino acids called polypeptide. Titin is a known largest polypeptide. This molecule extends from thick filament of muscle to the Z disc. This acts as spring to keep the thick filament at the center of the sarcomere. Titin is made up of 89 amino acids,. The polypeptide has repeated immunoglobulin sequences.

D.

Summary Introduction

To explain: The reason that the force collapse so abruptly after each peak.

Introduction: Protein is a biomolecule. It consists of a chain of amino acids called polypeptide. Titin is a known largest polypeptide. This molecule extends from thick filament of muscle to the Z disc. This acts as spring to keep the thick filament at the center of the sarcomere. Titin is made up of 89 amino acids,. The polypeptide has repeated immunoglobulin sequences.