Concept explainers
(a)
Interpretation:
The steps required to obtain the pure samples of the given compound from the starting material are to be stated.
Concept introduction:
The rearrangement in which acyl azides
Answer to Problem 23.60AP
The reaction route for the synthesis of the given product is shown below.
Explanation of Solution
The separation of enantiomers occurs in three steps.
In the first step, the two enantiomers,
The separation of the two enantiomers is shown below.
Figure 1
The formation of the given product follows the curtius rearrangement. The reaction follows a concerted mechanism, a reaction in which the bond formation and bond dissociation occurs in a single step.
The
The reaction for the formation of
Figure 2
The desired product,
(b)
Interpretation:
The steps required to obtain the pure samples of the given compound from the starting material are to be stated.
Concept introduction:
An ester is formed by the reaction of carboxylic with alcohol in the presence of an acid catalyst. This reaction is known as Esterification.
Ester is the functional group which is formed from the reaction of an alcohol and a carboxylic acid. Esters end with a suffix,
Answer to Problem 23.60AP
The reaction route for the synthesis of the given product is shown below.
Explanation of Solution
The
The reaction of the formation of
Figure 3
The formation of
(c)
Interpretation:
The steps required to obtain the pure samples of the given compound from the starting material are to be stated.
Concept introduction:
Hofmann rearrangement reaction is the conversion reaction of the primary amide to a primary amine with the loss of one carbon chain. The reaction requires basic conditions. The reaction of sodium hydroxide with bromine forms sodium hypobromite as an intermediate in situ.
Answer to Problem 23.60AP
The reaction route for the synthesis of the given product is shown below.
Explanation of Solution
The isomer,
The reaction of the formation of
Figure 4
The formation of
(d)
Interpretation:
The steps required to obtain the pure samples of the given compound from the starting material are to be stated.
Concept introduction:
Hofmann rearrangement reaction is the conversion reaction of the primary amide to a primary amine with the loss of one carbon chain. The reaction requires basic conditions. The reaction of sodium hydroxide with bromine forms sodium hypobromite as an intermediate in situ.
Answer to Problem 23.60AP
The reaction route for the synthesis of the given product is shown below.
Explanation of Solution
The isomer,
The reaction of the formation of
Figure 5
The formation of
(e)
Interpretation:
The steps required to obtain the pure samples of the given compound from the starting material are to be stated.
Concept introduction:
Hofmann rearrangement reaction is the conversion reaction of the primary amide to a primary amine with the loss of one carbon chain. The reaction requires basic conditions. The reaction of sodium hydroxide with bromine forms sodium hypobromite as an intermediate in situ.
Answer to Problem 23.60AP
The reaction route for the synthesis of the given product is shown below.
Explanation of Solution
The isomer,
The reaction of the formation of
Figure 6
The formation of
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Chapter 23 Solutions
Organic Chemistry
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- Organic ChemistryChemistryISBN:9781305580350Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. FootePublisher:Cengage Learning