FUNDAMENTALS OF ANATOMY AND PHYSIOLOGY
11th Edition
ISBN: 2818440070945
Author: Martini
Publisher: PEARSON C
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Chapter 22, Problem 5RQ
Summary Introduction
Introduction:
Major Histocompatibility complex or MHC molecules are a class of cell surface proteins which are encoded by a set of genes. These molecules act as markers and help B-cell and T-cell receptors to recognize the self and foreign molecules and hence are the important component of the immune system.
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Which of the following statements is not true?(A) An antibody has more than one antigen-binding site.(B) A lymphocyte has receptors for multiple differentantigens.(C) An antigen can have different epitopes.(D) A liver or muscle cell makes one class of MHC molecule.
The cells illustrated below are examples of:
Choose from the following:
(A) potential antigen-presenting cells
(B) potential cells active in humoral immunity (synthesizing antibodies)
(C) potential cells active in cell-mediated immunity (T lymphocytes
(D) potential reticular cells
Immune system of humans
a) Secreted B cell receptors can function as opsonins.
b) MHC class II molecules can be found on the surface of nearly every cell of the body.
c) The membrane attack complex (MAC) is used by natural killer cells to eliminate virus infected host cells.
d) Both (a) and (b) are correct and (c) is incorrect
e) Statements (a), (b) and (c) are all correct
Chapter 22 Solutions
FUNDAMENTALS OF ANATOMY AND PHYSIOLOGY
Ch. 22 - Define pathogen.Ch. 22 - Prob. 2CPCh. 22 - How would blockage of the thoracic duct affect...Ch. 22 - Prob. 4CPCh. 22 - Prob. 5CPCh. 22 - Prob. 6CPCh. 22 - Prob. 7CPCh. 22 - Prob. 8CPCh. 22 - Prob. 9CPCh. 22 - What effects do pyrogens have in the body?
Ch. 22 - Explain the difference between cell-mediated...Ch. 22 - Prob. 12CPCh. 22 - Prob. 13CPCh. 22 - Prob. 14CPCh. 22 - How can the presence of an abnormal peptide in the...Ch. 22 - A decrease in the number of cytotoxic T cells...Ch. 22 - How would a lack of helper T cells affect the...Ch. 22 - Prob. 18CPCh. 22 - Prob. 19CPCh. 22 - Prob. 20CPCh. 22 - Which would be more negatively affectedthe primary...Ch. 22 - Which kind of immunity protects a developing...Ch. 22 - How does increased stress reduce the effectiveness...Ch. 22 - Prob. 24CPCh. 22 - Prob. 25CPCh. 22 - What may account for the increased incidence of...Ch. 22 - Prob. 27CPCh. 22 - Prob. 28CPCh. 22 - LEVEL 1 Reviewing Facts and Terms 1. Identify the...Ch. 22 - Prob. 2RQCh. 22 - Anatomically, lymphatic vessels resemble (a)...Ch. 22 - Prob. 4RQCh. 22 - Prob. 5RQCh. 22 - Prob. 6RQCh. 22 - Phagocytes move through capillary walls by...Ch. 22 - Prob. 8RQCh. 22 - Prob. 9RQCh. 22 - Prob. 10RQCh. 22 - CD4 markers are associated with (a) cytotoxic T...Ch. 22 - Prob. 12RQCh. 22 - Prob. 13RQCh. 22 - What are the three classes of lymphocytes, and...Ch. 22 - What seven defenses present at birth provide the...Ch. 22 - Compared with innate defenses adaptive defenses...Ch. 22 - Prob. 17RQCh. 22 - A decrease in which population of lymphocytes...Ch. 22 - Skin tests are used to determine if a person (a)...Ch. 22 - Compare and contrast the effects of complement...Ch. 22 - How does a cytotoxic T cell destroy another cell...Ch. 22 - How does the formation of an antigen-antibody...Ch. 22 - Give one example of each type of immunity: innate...Ch. 22 - Prob. 24RQCh. 22 - An investigator at a crime scene discovers some...Ch. 22 - Ted finds out that he has been exposed to measles....Ch. 22 - While walking along the street, you and your...Ch. 22 - Paulas grandfather is diagnosed as having lung...Ch. 22 - Willy is allergic to ragweed pollen and tells you...Ch. 22 - Prob. 1CCCh. 22 - Does baby Ruthie still need her chickenpox vaccine...
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- The major histocompatibility complex (MHC) (a) consists of Y-shaped molecules (b) encodes certain antibodies (c) encodes Toll-like receptors (d) inhibits complement release from macrophages (e) encodes a group ofcell-surface proteins.arrow_forwardThe human immune system includes a number of specialized cells. Suggest the activity of the macrophage based on your understanding of cell processes. The macrophage • a) produces large antibody proteins. 9 • b) uses pinocytosis to drink solutes. . 12 • c) engulfs and digests bacteria and other pathogens 15 d) has specific receptor proteins that allow the capture of antigens.arrow_forwardAn antigen that overstimulates the immune system bybonding nonspecifically to MHC on antigen-presenting cells istermed a:(a) Nonspecific antigen (d) Toxic shock syndrome(b) Superantigen (e) Super necrotic(c) Epitopearrow_forward
- T cells and B cells can be activated only by, (a) pathogenic microorganisms.(b) interleukins, interferons, and colony-stimulating factors. (c) cells infected with viruses, bacterial cells, or cancer cells. (d) exposure to a specific antigen bound to a MHC protein on a plasma membrane.arrow_forwardWhich of the following should be the same inidentical twins?(A) the set of antibodies produced(B) the set of MHC molecules produced(C) the set of T cell antigen receptors produced(D) the set of immune cells eliminated as self-reactivearrow_forwardUse the following choices for the next set of questions. A choice may be used zero or more times: a)MHC class I b) MHC class Il C) both MHC class I and II d) neither MHC class | or II e) cannot be determined 21) expressed on T cells 22) captures antigens present in endosomes 23) strongly affected by proteasomal inhibition 24) downregulated by many viruses 25) the genes responsible for expression are monomorphic, meaning that identical alleles are shared throughout the populationarrow_forward
- CTLs use the following membrane-bound protein interactions to “kill” a target cell through apoptosis: Question 8 options: A) IL-2/IL-2 receptor B) CD4/MHC II C) TCR/MHC II D) Fas/FasLarrow_forwardVaccination increases the number of(A) different receptors that recognize a pathogen.(B) lymphocytes with receptors that can bind to the pathogen.(C) epitopes that the immune system can recognize.(D) MHC molecules that can present an antigenarrow_forwardThe brain can sense cytokines released by peripheral immune cells through the following means EXCEPT a.) Cytokines being transported across the blood-brain barrier b.) Cytokines crossing intact blood-brain barrier by diffusion c.) Cytokines circumventing blood-brain barrier at circumventricular organs d.) Cytokines activating general visceral sensory nervesarrow_forward
- Which of the following is NOT true about T cells?(a) T cells develop from lymphoid stem cells in the bonemarrow and mature in the thymus.(b) Cell-mediated immunity is primarily carried out by Tcells.(c) Subsequent differentiation of T cells produces cytotoxic(killer) T cells, delayed-hypersensitivity T cells, helper Tcells, and regulatory T cells.(d) Natural killer cells (NK) are exclusively differentiated Tcells.(e) T cells act in situations where antigens are embeddedin cell membranes or are inside host cells and thus areinaccessible to antibodies.arrow_forward1. (a) (b) (c) (d) (e) (f) (g) (h) Provide the word that best fits the definition for each part below. A protein on the surface of macrophages and other immune cells that recognizes and binds the constant regions of antibodies in antibody-antigen complexes. The portion of an antigen that is recognized by a particular antibody. An antibody that is produced by a hybridoma, a hybrid between a normal B cell and a B cell tumor. A pharmaceutical product that is produced from living organisms or contains components of living organisms. Description of a monoclonal antibody that has been engineered to have the original murine variable regions of the heavy and light chains coupled with human constant regions of the heavy and light chains. A generic form of a biologic drug. It is not identical in structure but identical in function, side effects, and toxicity. A new cancer therapy in which the tail end of an anti-cancer antibody is replaced by a T cell. Binding of the antibody to the tumor can…arrow_forwardWhich of the following immune cells/molecules are most ef-fective at destroying intracellular pathogens?(a) TH cells (d) B cells(b) Antibodies (e) Complement(c) TC cellsarrow_forward
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