Biology
5th Edition
ISBN: 9781260487947
Author: BROOKER
Publisher: MCG
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Chapter 2.2, Problem 1CC
Summary Introduction
To describe: The process of separation of DNA strands requires energy or it is just a spontaneous process.
Introduction: The DNA stands for “deoxyribonucleic acid.” Structure of DNA is made up of a number of monomers called
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Consider the following segment of DNA, which is part of a linear chromosome:
LEFT 5’.…TGACTGACAGTC….3’
3’.…ACTGACTGTCAG….5’ RIGHT
During DNA replication, this double-strand molecule is separated from the right to the left into two single strands and the replisome is moving from the right to the left of the segment. ___________ should be the template for the lagging strand synthesis.
neither of the two strands
the bottom strand
both top and bottom strands
the top strand
Consider the following segment of DNA, which is part of a linear chromosome:
LEFT 5’.…TGACTGACAGTC….3’
3’.…ACTGACTGTCAG….5’ RIGHT
During DNA replication, this double-strand molecule is separated from the right to the left into two single strands and the replisome is moving from the right to the left of the segment. The replisome is approaching to a chromosomal end on the left. Considering this left chromosomal end, if without telomerase, the newly synthesized daughter DNA of ___________ will be shortened?
neither top or bottom strand
both top and bottom strands
the top strand
the bottom strand
Imagine you are able to incorporate a heavy isotope into the atoms of both strands of double
stranded DNA. When these strands are replicated, the daughter strands do not contain the label.
After two generations of semi-conservative DNA replication, how many single strand pieces of
DNA will contain that label, if you only consider the products the second generations? Hint...draw
it out!
One set of paired labeled strands and 3 sets of paired non-labeled strands for 4 double-stranded pieces of
DNA total
Four sets of 1 labeled strand paired with 1 non-labeled strand for 4 double-stranded pieces of DNA total
OTwo sets of paired labeled strands and 6 sets of paired non-labeled strands for 8 double-stranded pieces of
DNA total
OTwo sets of 1 labeled strand paired with 1 non-labeled strand, and 2 sets of paired non-labeled strands for 4
double-stranded pieces of DNA total
Chapter 2 Solutions
Biology
Ch. 2.1 - Before the experiment conducted by Ernest...Ch. 2.1 - What was the hypothesis tested by Rutherford?Ch. 2.1 - Prob. 3EQCh. 2.1 - Explain the difference between an electron shell...Ch. 2.2 - Core Skill: Modeling The goal of this modeling...Ch. 2.2 - Prob. 1CCCh. 2.3 - When oil dissolves in a soapy solution, where is...Ch. 2.4 - Core Skill: Connections Look ahead to Figure...Ch. 2 - _______________ make(s) up the nucleus of an atom....Ch. 2 - Prob. 2TY
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- In an experiment, you grow bacterial cells for several generations in the presence of a light isotope of carbon (C¹2) and then transfer them into a medium containing a heavy isotope of carbon (C¹³). After one round of DNA replication, which of the following statements is true? O All DNA molecules will be labeled entirely with C¹3 ● For all DNA molecules, each strand will be labeled with a mixture of C¹2 and C¹³. Half the DNA molecules will be labeled with C¹2 only, whereas the other half will be labeled with C¹3 only. O All DNA molecules will be labeled entirely with C¹2 O For all DNA molecules, one strand will be entirely labeled with C¹2, whereas the other strand will be entirely labeled with C¹3 O Insufficient information to conclude.arrow_forwardWhich of the followings statements are true about DNA polymerase? 1.) It can only go in one direction, meaning the lagging strand can't be synthesized continuously. 2.) It cannot start a DNA strand from scratch, so another enzyme is needed to create "primers" as a starting point. 3.) It cannot copy epigenetic marks (such as methyl groups) on its own; these must be "copied" onto the daughter DNA strand by other enzymes after DNA replication. 4.) All of the abovearrow_forwardThe statement “DNA replicates by a semiconservative mechanism” means that (a) only one DNA strand is copied (b) first one DNA strand is copied and then the other strand is copied (c) the two strands of a double helix have identical base sequences (d) some portions of a single DNA strand are old and other portions are newly synthesized (e) each double helix consists of one old and one newly synthesized strandarrow_forward
- One strand of a single DNA helix is labeled red while the other strand of the same DNA helix is labeled blue. This double helix DNA is replicated through the process of semi-conservative replication. Note that a completely newly synthesized strand of DNA will be white. After three rounds of DNA replication, how many all-white DNA (both strands are white) will there be? Explain your reasoning.arrow_forwardAssume a deletion occurs in a gene that encodes DNA polymerase I and no functional DNA polymerase I is produced. What will be the most likely consequence of this mutation? The DNA would not exist in a supercoiled state. There would be no RNA primers laid down. The DNA will not be able to unwind to initiate replication. The DNA strands would contain pieces of RNA. There would be no DNA replication on the leading or lagging strands.arrow_forwardWhich of the following things must happen first if DNA is going to be replicated * DNA gets broken into smaller pieces to make the process more manageable DNA gets unzipped, so the two complimentary strands are separated DNA Polymerase adds on bases that match with the original strand DNA gets wound back into chromosomes so it's ready for mitosis Lenovo esc -> 女 # 2$ 2 3 5 6 7 8 9. tab e r t y a f k ift V alt ctriarrow_forward
- Which of the following statements about the DNA replication is false? a. Synthesis of the new DNA strands is form 39 to 59 b.Synthesis of the new DNA strands is from 59 to 39 c. DNA Unwinds, primase adds RNA primer, DNA polymerases synthesize the new strand and remove the RNA primer d. Many initiation points exist in each eukaryotic chromosome. e. Okazaki fragments are synthesized in the opposite direction from the direction in which the replication for moves.arrow_forwardConsider the following segment of DNA, which is part of a linear chromosome: LEFT 5’.…TGACTGACAGTC….3’ 3’.…ACTGACTGTCAG….5’ RIGHT During RNA transcription, this double-strand DNA molecule is separated into two single strands from the right to the left and the RNA polymerase is also moving from the right to the left of the segment. _____________ is the template strand for the synthesis of RNA? The sequence of the newly transcribed mRNA is _________________. Question 5 options: The top strand, 5'...GACUGUCAGUCA...3' The bottom strand, 5'...ACUCACUCUCAG...3' The top strand, 5'...UGACUGACAGUC...3' The bottom strand, 5'...GACUGUCAGUCA...3'arrow_forward4.) During DNA replication, the two strands of DNA are pried apart and then serve as templates for synthesis of new strands. However, there are some big differences in how the two strands are copied. Why is this so? Please describe in 4-5 sentences of your own words how replication proceeds on the two strands. 5.) During meiosis, when crossing-over occurs between two homologous chromosomes, it does not happen at a single point, but rather two points with a stretch of DNA in between. What are the two junction points called? b. What is the region between the two points called and what is different about this region compared to how double-stranded DNA usually is? c. If the region described in b.) is located within a gene and the two homologues have different alleles of this gene, what might happen that is a direct violation of Mendel's first law? (Describe the process with 2-3 sentences of detail.) a.arrow_forward
- During replication of a DNA molecule, the daughter strands are not produced in exactly the same manner. One strand, the leading strand, is made continuously toward the replication fork, while the lagging strand is made in fragments in the opposite direction. This difference in synthesis of the two strands is the result of which of the following? O a. DNA polymerase is not efficient enough to make two "good" strands of DNA O b. The two template strands are antiparallel, and DNA polymerase can only synthesize DNA in the 5' to 3' direction O c. The lagging strand is the result of DNA breaks caused by exposure to UV light Od. The cell does not contain enough nucleotides to make two complete strands Oe. Both B&Darrow_forward"Unlike what happens in DNA replication, where both strands are copied, only one of the two strands is transcribed into MRNA. The DNA strand that contains the gene is sometimes called the sense strand, or coding strand, and the DNA strand that gets transcribed to give RNA is called the antisense strand, or noncoding strand. Because the sense strand and the antisense strand are complementary, and because the DNA antisense strand and the newly formed RNA strand are also complementary, the RNA molecule produced during transcription is a copy of the DNA sense strand... The only difference is that the RNA molecule has a U everywhere the DNA sense strand has a T." Consider the following segment of a DNA sense strand: (5') CAA-ACT-ACG-GCG-TTG-CAG (3’)arrow_forwardOnce the strands have been replicated, the enzyme DNA polymerase I “cleans up” by removing the primers. Why must the primers be removed? Finally, the enzyme DNA ligase finishes up. What does DNA ligase do?arrow_forward
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