Practice of Statistics in the Life Sciences
Practice of Statistics in the Life Sciences
4th Edition
ISBN: 9781319013370
Author: Brigitte Baldi, David S. Moore
Publisher: W. H. Freeman
Question
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Chapter 20, Problem 20.5AYK

(a)

To determine

To define the individuals studied, the type of study and the explanatory and response variables and also find whether the variables are quantitative or categorical.

(a)

Expert Solution
Check Mark

Answer to Problem 20.5AYK

The individuals studied are infants with severe respiratory distress, the type of the study is randomized experiment, the explanatory variable is treatment provided to infants and the response variables is the infant survival and also the variables are quantitative.

Explanation of Solution

In the question, it is given that there are safe and effective interventions to treat respiratory failure in new-borns but they are typically costly. Researchers compared the survival of infants with severe respiratory distress who were treated at random either with the new bCPAP machine or nasal oxygen therapy, serving as a control. The published findings report that survival rate for neonates receiving bCPAP was 71%(4462) compared with 44%(1125) for controls. Thus, we can see that the individuals studied are infants with severe respiratory distress, the type of the study is randomized experiment. The explanatory variable is treatment provided to infants and the response variables is the infant survival. Also, we find out that the variables are quantitative.

(b)

To determine

To state the corresponding null and alternative hypotheses using mathematical symbols.

(b)

Expert Solution
Check Mark

Answer to Problem 20.5AYK

  H0:pbCPAP=pcontrolHa:pbCPAP>pcontrol

Explanation of Solution

In the question, it is given that there are safe and effective interventions to treat respiratory failure in new-borns but they are typically costly. Researchers compared the survival of infants with severe respiratory distress who were treated at random either with the new bCPAP machine or nasal oxygen therapy, serving as a control. The published findings report that survival rate for neonates receiving bCPAP was 71%(4462) compared with 44%(1125) for controls. The researchers tested the hypothesis that the rate of survival was higher for babies receiving bCPAP than in control group. So, let the proportions for the bCPAP and the control group be p^bCPAP and p^control respectively. Thus, the null and alternative hypotheses using mathematical symbols can be defined as:

  H0:pbCPAP=pcontrolHa:pbCPAP>pcontrol

(c)

To determine

To check whether the conditions are met.

(c)

Expert Solution
Check Mark

Answer to Problem 20.5AYK

Yes, they are met.

Explanation of Solution

In the question, it is given that there are safe and effective interventions to treat respiratory failure in new-borns but they are typically costly. Researchers compared the survival of infants with severe respiratory distress who were treated at random either with the new bCPAP machine or nasal oxygen therapy, serving as a control. The published findings report that survival rate for neonates receiving bCPAP was 71%(4462) compared with 44%(1125) for controls. The researchers tested the hypothesis that the rate of survival was higher for babies receiving bCPAP than in control group. So, let the proportions for the bCPAP and the control group be p^bCPAP and p^control respectively. Thus, the null and alternative hypotheses using mathematical symbols can be defined as:

  H0:pbCPAP=pcontrolHa:pbCPAP>pcontrol

Thus, the conditions are met because the data are reasonably random and representative of the corresponding populations. Also, the counts of successes and failures in both the samples are large enough.

(d)

To determine

To obtain the test statistics and P-value and then conclude in context.

(d)

Expert Solution
Check Mark

Answer to Problem 20.5AYK

  z=2.36P=0.0091

So, we have sufficient evidence to conclude that the rate of survival is higher for babies receiving bCPAP than in control group.

Explanation of Solution

In the question, it is given that there are safe and effective interventions to treat respiratory failure in new-borns but they are typically costly. Researchers compared the survival of infants with severe respiratory distress who were treated at random either with the new bCPAP machine or nasal oxygen therapy, serving as a control. The published findings report that survival rate for neonates receiving bCPAP was 71%(4462) compared with 44%(1125) for controls. The researchers tested the hypothesis that the rate of survival was higher for babies receiving bCPAP than in control group. So, let the proportions for the bCPAP and the control group be p^bCPAP and p^control respectively. Thus, the null and alternative hypotheses using mathematical symbols can be defined as:

  H0:pbCPAP=pcontrolHa:pbCPAP>pcontrol

Thus, to do the mechanics of a hypothesis test for equality of population proportions we will use the calculator TI89 . Then select 6:2 PropZTest from the STAT Tests menu. Enter the observed counts and sample sizes. Indicate what kind of test you want: one-tail upper tail, lower tail, or two-tail. And specify whether results should simply be calculated or displayed with the area corresponding to the P-value of the test shaded. Thus, we know that,

  p^bCPAP=x1n1=4462=0.71p^control=x2n2=1125=0.44

Thus, by using the calculator TI89 , the test statistics and the P-value is as:

  z=2.36P=0.0091

As we know that if the P-value is less than or equal to the significance level then the null hypothesis is rejected, so we have,

  P<0.05Reject H0

Thus, we have sufficient evidence to conclude that the rate of survival is higher for babies receiving bCPAP than in control group.

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