Human Anatomy & Physiology Plus Mastering A&P with Pearson eText -- Access Card Package (2nd Edition) (What's New in Anatomy & Physiology)
2nd Edition
ISBN: 9780134702339
Author: Erin C. Amerman
Publisher: PEARSON
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Textbook Question
Chapter 20, Problem 16CYR
Which of the following is not a role of TH cells?
a. Stimulation of macrophages
b. Activation of naïve TC cells
c. Stimulation of naïve B cells
d. Stimulation of clonal selection
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Which of the following explains why dendritic cells, but not macrophages or B cells, contribute to the activation of naive T cells?
a. Macrophages and B cells do not express MHC class II molecules until they are activated.
b. Dendritic cells upregulate B7 after engaging innate immunity receptors at sites of infection.
c. Dendritic cells express higher levels of CTLA4.
d. Macrophages and B cells do not process antigen.
e. Dendritic cells use Toll-like receptors to hold antigen in place for extended periods of time.
Which of the following statements about T cells is false? a. Helper T cells release cytokines while cytotoxic T cells kill the infected cell. b. Helper T cells are CD4+, while cytotoxic T cells are CD8+. c. MHC II is a receptor found on most body cells, while MHC I is a receptor found on immune cells only. d. The T cell receptor is found on both CD4+ and CD8+ T cells.
Explain why each choice (a-d) is correct or incorrect.
T cells are differentiated into two groups based on their glycoproteins CD4 or CD8. Which of the following is true of CD4 T cells?
a. They become cytotoxic T cells.
b. The become antigen presenting cells.
c. They become T helper cells.
d. They become plasma cells.
Chapter 20 Solutions
Human Anatomy & Physiology Plus Mastering A&P with Pearson eText -- Access Card Package (2nd Edition) (What's New in Anatomy & Physiology)
Ch. 20.1 - What are the main functions of the lymphatic...Ch. 20.1 - 2. How do lymphatic capillaries differ from blood...Ch. 20.1 - What is the pathway of lymph flow from the right...Ch. 20.1 - 4. What main cell types are located in lymphoid...Ch. 20.1 - List the main functions of MALT, lymph nodes, the...Ch. 20.2 - 1. How do innate immunity and adaptive immunity...Ch. 20.2 - 2. What are the three lines of defense?
Ch. 20.2 - What are the bodys main surface barriers, and how...Ch. 20.2 - Prob. 4QCCh. 20.2 - How are the immune system and lymphatic system...
Ch. 20.3 - Match the following cell types with their correct...Ch. 20.3 - Which of the cells in question 1 do not directly...Ch. 20.3 - What is the complement system, and what are its...Ch. 20.3 - In what two ways is the complement system...Ch. 20.3 - 5. What are the main cytokines of innate...Ch. 20.3 - What are the four cardinal signs of inflammation?Ch. 20.3 - 7. What are inflammatory mediators, and what do...Ch. 20.3 - Explain the role of phagocytes in the inflammatory...Ch. 20.3 - What causes the elevated temperature and common...Ch. 20.3 - Prob. 10QCCh. 20.4 - 1. What are MHC molecules?
Ch. 20.4 - 2. How do class I and class II MHC molecules...Ch. 20.4 - How are T cells activated?Ch. 20.4 - Prob. 4QCCh. 20.4 - What are the main functions of TC cells?Ch. 20.4 - Prob. 6QCCh. 20.4 - Prob. 7QCCh. 20.5 - 1. How is a B cell activated?
Ch. 20.5 - Prob. 2QCCh. 20.5 - What are the five classes of antibody, and how do...Ch. 20.5 - 4. List the five main functions of antibodies.
Ch. 20.5 - How do the primary and secondary immune responses...Ch. 20.5 - 6. What is the purpose of a vaccination, and what...Ch. 20.5 - 7. How do active immunity and passive immunity...Ch. 20.6 - How do innate immunity and adaptive immunity work...Ch. 20.6 - Walk through the basic steps of the immune...Ch. 20.6 - How does the immune system survey the body for...Ch. 20.6 - Walk through the steps of the immune response to...Ch. 20.6 - Prob. 5QCCh. 20.6 - 6. How do cancer cells escape the immune response...Ch. 20.7 - Define the four types of hypersensitivity...Ch. 20.7 - Explain how type IV hypersensitivity differs from...Ch. 20.7 - How do primary and secondary immunodeficiency...Ch. 20.7 - Prob. 4QCCh. 20.7 - What is an autoimmune disorder? What produces the...Ch. 20.7 - 6. What are the potential causes of autoimmune...Ch. 20 - 1. Which of the following is not a function of the...Ch. 20 - Mark the following statements as true or false. If...Ch. 20 - Fill in the blanks: The lymphoid organ that...Ch. 20 - Fill in the blanks: Nonspecific immunity is also...Ch. 20 -
5. Which of the following make up the body’s...Ch. 20 - Which of the following does not describe the...Ch. 20 - Mark the following statements as true or false. If...Ch. 20 - Which of the following functions is/are performed...Ch. 20 - Prob. 9CYRCh. 20 - 10. When naïve B cells are activated, they...Ch. 20 - 11. Match the following antibodies with the...Ch. 20 - Mark the following statements as true or false. If...Ch. 20 - Prob. 13CYRCh. 20 - On which type(s) of cells are class I MHC...Ch. 20 - Fill in the blanks: Class I MHC molecules display...Ch. 20 - 16. Which of the following is not a role of TH...Ch. 20 - 17. Mark the following statements as true or...Ch. 20 - 18. Type I hypersensitivity is due to release of...Ch. 20 - Prob. 19CYRCh. 20 - Prob. 20CYRCh. 20 - Prob. 1CYUCh. 20 - Complement proteins are crucial for stimulating...Ch. 20 - 3. Terrence has severe asthma and allergies, and...Ch. 20 - Your friend tests her snake-wrangling skills on an...Ch. 20 - 2. Carla presents to her physician with a...Ch. 20 - 3. Mr. White has been diagnosed with febrile...Ch. 20 - Mr. White developed neutropenia as a consequence...Ch. 20 - 5. The chemotherapeutic drugs Mr. White is taking...
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- Explain why each choice (a-d) is correct or incorrect. Which statement is true about T cells? a. They usually directly recognize antigens, which then activates a subpopulation of killer cells b. Their proliferation is enhanced by interleukins 1 and 2. c. Once activated, they cannot secrete cytokines. d. They will develop into cytotoxic T cells if antigen is complexed with class II MHC proteins.arrow_forwardExplain why each choice (a-d) is correct or incorrect. In order for an antigen to activate or sensitize a T helper cell, the antigen must be a. coated with antibodies b. displayed on the surface of an APC along with MHC antigens c. displayed on the surface of another T cell with IgD antibodies d. partly digested by a natural killer cellarrow_forwardThe immune system includes the various responses the body uses to ensure survival in the presence of disease-causing agents. Identify the example of innate immunity. A. Infected host cells are killed by toxic proteins from cytotoxic T cells. B. Toll-like receptors bind to foreign molecule fragments to initiate immune response. C. CD4 accessory proteins on the helper T cell surface bind to class II MHC molecules. D. IgE antibodies recognize and attach to pollen grains, stimulating an allergic reaction.arrow_forward
- Which of the following is NOT true about T cells? A. Natural killer cells (NK) are exclusively differentiated T cells B. T cells act in situations where antigens are embedded in cell membranes or are inside host cells and thus are inaccessible to antibodies C. T cells develop from lymphoid stem cells in bone marrow and mature in the thymus D. Cell-mediated immunity is primarily carried out by T cellsarrow_forwardSuppose a person recovers normally from viral infections, but then gets the same viral infections over and over again- unlike the rest of us. A. What is probably wrong –B cells, helper T cells and/or cytotoxic T cells? B. Should this person be at a higher risk of cancer than the rest of us? C. Should this person be able to lyse bacterial cells as well as the rest of us? D. Should this person tolerate a graft (from an unreated person) better than you are me?arrow_forwardWhich of the following statements regarding T cells activated by specific antigen is incorrect? a. They receive co-stimulatory signals through CD28. b. They suppress expression of sphingosine 1-phosphate (SIP). c. They take several days before differentiating into effector T cells. d. They cease to secrete and respond to interleukin-2 (IL-2). e. They begin to express CTLA4, which serves to limit T-cell proliferation.arrow_forward
- Which of the following pairs is mismatched? a. T-cell activation: cell division and differentiation b. effector B cell: plasma cell c. plasma cell: antibody secretion d. helper T cell: kills pathogen-infected cells e. helper T cell: facilitates the differentiation of B cells.arrow_forwardWhich of the following is part of the second line of defense against pathogens?a. skin b. mucus membranesc. lysozyme in tears d. phagocytes Which of the following does NOT have MHC class II molecules on the surface of their cell membranes? a. Macrophages.b. Dendritic cells.c. B cells.d. Helper T cells.arrow_forwardHoming of effector T cells to inflamed tissue is facilitated by the upregulation of _____ on the surface of the effector T cell. a. VLA-4 b. L-selectin c. CD28 d. VCAM-1 e. B7.arrow_forward
- What is the predicted outcome if a patient receives an allogeneic hematopoietic cell transplant from a family member, and then receives a kidney transplant several months later from the same donor? a. Acute kidney rejection because the patient’s hematopoietic system has been fully reconstituted with patient-derived alloreactive T cells and NK cells. b. Graft-versus-host disease mediated by alloreactive T cells in the transplanted kidney. c. Secondary immune response by patient-derived memory T lymphocytes that were initially activated by the hematopoietic cell transplant. d. The patient is tolerant to alloantigens on the kidney graft and does not require long-term immunosuppressive drugs.arrow_forwardWhich of the following pairs is mismatched? a. plasma cell: mediation of phagocytosis and killing of microorganisms in the plasma b. megakaryocyte: formation of platelets c. dendritic cell: activation of adaptive immune responses d. natural killer cell: develops from a common lymphoid progenitor e. neutrophil: formation of pus f. regulatory T cell: inhibition of T-cell activity.arrow_forwardTo become a fully activated, antibody-secreting cell, B cells usually need: a. to encounter an antigen or receive a signal delivered by a helper T cell. b. to ingest a foreign invader such as a microobe. c. activation by a plasma cell d. contact with an antigen and helper T cell cytokinesarrow_forward
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