Biological Science, Books a la Carte Plus Mastering Biology with Pearson eText -- Access Card Package (6th Edition)
6th Edition
ISBN: 9780134296029
Author: Scott Freeman, Kim Quillin, Lizabeth Allison, Michael Black, Greg Podgorski, Emily Taylor, Jeff Carmichael
Publisher: PEARSON
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Chapter 19, Problem 7TYU
Summary Introduction
To review:
The activity of the drug inhibiting the histone deacetylase (HDAC) on the gene expression.
Introduction:
The deoxyribonucleic acid (DNA) must be separated from the histone proteins for the ribonucleic acid (RNA) polymerases to get attach to DNA template for initiation of transcription.
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Chapter 19 Solutions
Biological Science, Books a la Carte Plus Mastering Biology with Pearson eText -- Access Card Package (6th Edition)
Ch. 19 - What is chromatin? a. the histone-containing...Ch. 19 - Prob. 2TYKCh. 19 - Prob. 3TYKCh. 19 - Prob. 4TYKCh. 19 - Compare and contrast the items in each pair: (a)...Ch. 19 - Prob. 6TYUCh. 19 - Prob. 7TYUCh. 19 - Prob. 8TYUCh. 19 - Prob. 9TYPSSCh. 19 - 10. QUANTITATIVE Imagine repeating the experiment...
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- Determine whether the following will increase or decrease gene expression: mRNA degradation mRNA capping Binding of a transcriptional activator Ubiquitination of a protein and targeting to the proteasomearrow_forwardBriefly explain how different modifications of histone protein affects the epigenetics of a genearrow_forwardWhich mechanisms for regulating gene expression may be applied for the treatment of such diseases? Propose a method of treatment. Explain how it might work.  Reference: https://link.springer.com/article/10.1186/ar3317arrow_forward
- Post-translational control refers to: a. regulation of gene expression after transcription b. regulation of gene expression after translation c. control of epigenetic activation d. period between transcription and translationarrow_forwardNew drugs are being developed that decrease DNA methylation and prevent the removal of acetyl groups from histone proteins. Explain how these drugs could affect gene expression to help kill tumor cells.arrow_forwardExplain Phenotypes of mutations in genes encoding transcription factors.arrow_forward
- List and discuss four different mechanisms by which vitamins A and D regulate gene expression.arrow_forwardwhat is the role and relevence of chromatin in gene expressionarrow_forwardExplain how a gene knockdown reagent, such as RNAi or a morpholino, could interfere with expression of a gene without affecting the rate of transcription of the target gene.arrow_forward
- Covalent modification of eukaryotic DNA is an important regulator of gene expression. Name one type of covalent modification of DNA. Describe the location of this modification and the effect on gene expression.arrow_forwardDefine regulatory mutation. Describe how an insertion, deletion, or substituion of a base pair in a promoter might affect the transcription driven by that promoter.arrow_forwardExplain how the genetic code is used in the expression of a gene.arrow_forward
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