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Chapter 19, Problem 7TY
Summary Introduction

Introduction:

Traits that are governed by the interaction of different alleles and genes, those traits are termed as polygenic. In this case, there is no concept of complete dominance. All the genes contribute equally to a trait.

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Which of the following does not have an environmental factor thataffects the distribution of the phenotype? a. phenylketonuria                        c. heightb. skin color                                  d. Marfan syndrome
Phenylketonuria (PKU) is a human hereditary disease resulting from the inability of the body to process the chemical phenylalanine, which is contained in the protein we eat. PKU is manifest in early infancy and, if it remains untreated, generally leads to cognitive impairment. PKU is caused by a recessive allele with simple Mendelian inheritance. A couple intends to have children but consults a genetic counselor because the man has a sister with PKU and the woman has a brother with PKU. There are no other known cases in their families. They ask the genetic counselor to determine the probability that their first child will have PKU. What is this probability?
Phenylketonuria (PKU) is an inherited disease caused by a recessive allele. Individuals with PKU have two recessive alleles and have very low levels of an enzyme that is needed to properly break down proteins. If a woman and her husband are both carriers and have three children, what is the probability of each of the following? Show your math. (Hint: You can represent your probabilities as fractions or decimals, but probabilities are always between 0 and 1) a. All three children are of normal phenotype.   b. One or more of the three children have the disease.   c.All three children have the disease.
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