Cardiopulmonary Anatomy & Physiology
7th Edition
ISBN: 9781337794909
Author: Des Jardins, Terry.
Publisher: Cengage Learning,
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Chapter 19, Problem 10RQ
The concentration of True _______ False _________
myoglobin in skeletal
muscles is decreased
in high-altitude
natives.
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The _____________ of hemoglobin is defined as the ratio of hemoglobin with bound oxygen to total hemoglobin.
Increasing concentrations of either 2,3-bisphosphoglycerate (BPG) or protons (H +) cause a ____________ ( rightward OR leftward) shift of the hemoglobin/oxygen binding curve. However, the mechanisms by which these two substances mediate this effect are distinct. Compare & contrast the way by which BPG and protons interact with hemoglobin and thereby influence its structure and function
True ____ False ____ The oxygen percentage decreases as an individual ascends a mountain
Chapter 19 Solutions
Cardiopulmonary Anatomy & Physiology
Ch. 19 - The barometric pressure is about half the...Ch. 19 - 2. The oxygen diffusion capacity of high-altitude...Ch. 19 - Prob. 3RQCh. 19 - Prob. 4RQCh. 19 - Prob. 5RQCh. 19 - At high altitude, the True _______ False ________...Ch. 19 - 7. In individuals who True ___________ False...Ch. 19 - 8. There is a linear True_______ False...Ch. 19 - 9. Natives who have been True ________...Ch. 19 - 10. The concentration of True _______ False...
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- Haemoglobin is also known as?arrow_forwardNotice that the person described in the flowchart is shivering, even though his body temperature is at the normal set point = 37°C. why he is shivering.arrow_forwardSuppose Gina climbs a high mountain where the oxygen partial pressure in the air decreases to 70 torr. Assume that the pH of her tissues and lungs is 7.4 and the oxygen concentration in her tissues is 20 torr. The P50 of hemoglobin is 26 torr. The degree of cooperativity of hemoglobin, n, is 2.8. Estimate the percentage of the oxygen-carrying capacity that she utilizes. Calculate your answer to one decimal place. сараcity: %arrow_forward
- At a pO 2 of ~100 torr, hemoglobin in whole blood is about 90% saturated with oxygen. This corresponds to ______________ pressure, where the ____________ of hemoglobin is favored.arrow_forwardLowering the pH from 7.4 to 6.8, which can occur during heavy respiration, reduces the Hill coefficient for oxygen binding to hemoglobin. True or Falsearrow_forwardIn 1913, Archibald Hill described an alternative formulation for cooperative processes such as the binding of oxygen by hemoglobin by considering the hypothetical equilibrium Hb+ n0₂ Hb(0₂)n 2 Analysis leads to the Hill equation: n p02₂" ( Y log (₁ x x ) = log Y (^_^) log where Y is the fractional saturation. This equation suggests that a plot of log with slope n. Plots for myoglobin and hemoglobin are shown here: 3 2 1 O -1 -2 -3 P50 + n = nlog (pO,) – n log(P5o) Myoglobin (0.25, -0.25) -1 0 1 2 log (pO₂) (3.0, 2.5) 3 4 (^_^) log 3 2 1 O -1 -2 -3 -4 (0, -3.4) -1 0 Y Y versus log (pO₂) should yield a line Hemoglobin (2.1, 2.5) - (0.7, -2.0) (1.9, 1.3) (0.4, -3.5) 1 2 log (pO₂) - (2.4, 2.4) 3 4arrow_forward
- To demonstrate an understanding of oxyhemoglobin binding, insert a word from the list in each blank to complete the statements. Not all terms will be used. increased A right shift of the oxy-hemoglobin curve signifies a affinity for oxygen. hold acidic A temperature will cause a right shift of the oxy- hemoglobin curve. basic A more pH than normal blood pH will cause a right shift higher of the oxy-hemoglobin curve. As a person exercises, their muscles give off heat which raises the temperature of the blood. This will cause hemoglobin to more oxygen at the cells. lower release decreasedarrow_forwardCarbon monoxide binds to the active site of hemoglobin and inhibits the binding of oxygen. This is an example of _________________________. Question 19 options: a competitive inhibitor denaturation a noncompetitive inhibitor an environmental inhibitorarrow_forwardThis is a three-part question You want to measure the blood oxygen level in a drop of blood using a pulse oximetry device. If you have a light source at 700nm, and 1mm of path length, what must be the concentration of: - oxidized hemoglobin in blood so that the light intensity at the output decreases to one tenth of the input intensity? - reduced hemoglobin in blood so that the light intensity at the output decreases to one tenth of the input intensity? - at the concentration you found in the second part, what is (Ii/If) for oxidized hemoglobin?arrow_forward
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