Biology: The Dynamic Science
4th Edition
ISBN: 9781337246422
Author: Peter J. Russell; Paul E. Hertz; Beverly McMillan
Publisher: Cengage Learning US
expand_more
expand_more
format_list_bulleted
Concept explainers
Question
Chapter 18, Problem 8TYK
Summary Introduction
Introduction:
Dolly is a female transgenic sheep, which is a product of reproductive cloning. It is an example of successful genetic engineering on a farm animal for the production of milk and milk products. Somatic cell gene therapy is employed in cloning Dolly through nuclear transfer.
Expert Solution & Answer
![Check Mark](/static/check-mark.png)
Want to see the full answer?
Check out a sample textbook solution![Blurred answer](/static/blurred-answer.jpg)
Students have asked these similar questions
The following diagram outlines how the process of cloning a sheep was accomplished. Cloning is the process of creating a genetically identical copy of another individual. With Dolly, the first cloned mammal, an egg cell was removed from a donor (B) and the nucleus was removed from the egg cell. Then cells from a sheep's mammary gland were removed from a second donor (A). The nucleus of one of the cells from the mammary gland was fused with the enucleated egg cell using an electrical pulse. The fused cell underwent cell division and at the blastocyst stage was implanted into a surrogate mother sheep. The percentage of genetic material that Dolly (the clone) had in common with Donor A is
Select one:
a. 25%
b. 50%
c. 100%
d. 0%
The key to the successful cloning of Dolly in 1994 wasa. extracting the nuclei from early-stage embryos.b. transferring the nuclei into nucleated eggs.c. starving the donor and recipient cells.d. employing surrogate mothers related to the nuclei donors
Dolly is the first mammal to have been successfully cloned from an adult cell Which of the following statement/s is/are most relevant to the birth of Dolly?
I. It suggests that human could be cloned.
II. It proves that specialized cells could be used to create an exact copy of the animal they came from.
III. It improves the production of milk, meat, and other products from livestock.
IV. It proves that animals could be cloned to have gene mutations that help scientists study diseases that develop in the animals.
A. II only
B. I and II
C. III, and IV
D. II, III, and IV
Which of the following statements best explain the significance of mitosis and ?
A. Both mitosis and meiosis produce diploid cells which responsible for the continuity of life.
B. Many single-celled organisms rely on mitosis and meiosis as their primary means of asexual reproduction
C. replication, cells have another interesting choice, whether they want to make an identical copy, or do they want to make four half-copies…
Chapter 18 Solutions
Biology: The Dynamic Science
Ch. 18.1 - What features do restriction enzymes have in...Ch. 18.1 - Prob. 2SBCh. 18.1 - What information and materials are needed to...Ch. 18.2 - What is a transgenic organism?Ch. 18.2 - Prob. 2SBCh. 18.3 - What is a restriction fragment length polymorphism...Ch. 18.3 - Prob. 2SBCh. 18.3 - Prob. 3SBCh. 18 - Prob. 1TYKCh. 18 - Prob. 2TYK
Ch. 18 - Why are antibiotic resistance markers such as ampR...Ch. 18 - After a polymerase chain reaction (PCR), agarose...Ch. 18 - A cDNA and a cloned fragment of genomic DNA share...Ch. 18 - Prob. 6TYKCh. 18 - Which of the following is not true of somatic cell...Ch. 18 - Prob. 8TYKCh. 18 - Prob. 9TYKCh. 18 - Prob. 10TYKCh. 18 - Prob. 11TYKCh. 18 - Discuss Concepts A forensic scientist obtained a...Ch. 18 - 13. Suppose a biotechnology company has developed...Ch. 18 - Prob. 14TYKCh. 18 - You learned in the chapter that an STR locus is a...
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Do all of them True/False 31) The process by which an electrical charge is used to introduce DNA into a cell to produce a transgenic organism is called electroporation.Answer: 32) Reproductive cloning is used to produce large amounts of mammalian proteins from transgenic agricultural animals such as cattle.Answer: 33) In gene addition, homologous recombination is used to remove the original gene and replace it with the cloned gene.Answer: 34) All stem cells have the potential to differentiateAnswer: 35) A bone marrow transplant involves the transfer of multipotent stem cellsAnswer: 36) The fact that in mammalian systems multiple genes may compensate for the loss of a gene is called gene redundancy.Answer:arrow_forwardFor each of the following scenarios, indicate YES (it is cloning) or NO (it is not cloning). 6. ___________ Sperm taken from a male goat is combined with a female's egg in a petri dish. The resulting embryo is implanted into the female's uterus to develop 7. ___________ A sheep embryo, composed of 16 cells, is removed from the mother's uterus and separated into individual cells. Each cell is allowed to multiply, creating 16 separate embryos, which are then implanted in different female sheep to develop to maturity. 8. ___________ A cow with many desirable traits is stimulated with hormones to produce a number of egg cells. Each of these eggs is fertilized and implanted into a surrogate mother. 9. ___________ Cell nuclei from a recently deceased dog are placed into enucleated egg cells from another female dog. These egg cells are then placed into the uterus of an additional female surrogate dog, where it grows into a puppy.arrow_forwardThere are two time gaps in the process of cloning. What are they? (ie. What do you have to wait for?)arrow_forward
- 5) Below is an image that shows both reproductive and therapeutic cloning. Use this image to answer compare and contrast therapeutic and reproductive cloning. Are they used for similar means…etc. Once you have done that answer the question below. a) There are two types of therapeutic cloning. What are they and how are they different?arrow_forwardWoolly mammoths have been extinct for about 10,000 years, but we often find their well- preserved remains in Siberian permafrost. Research groups are now planning to use SCNT to resurrect these huge elephant- like mammals. No mammoth eggs have been recovered so far, so elephant eggs would be used instead. An elephant would also be the surrogate mother for the resulting embryo. The researchers may try a modified SCNT technique used to clone a mouse that had been dead and frozen for sixteen years. Ice crystals that form during freezing break up cell membranes, so cells from the frozen mouse were in bad shape. Their DNA was transferred into donor mouse eggs, and cells from the resulting embryos were fused with mouse stem cells. Four healthy clones were born from the hybrid embryos. What are some of the pros and cons of cloning an extinct animal?arrow_forwardWith the use of well-illustrated diagrams, reconstruct the entire cloning process by explaining different stages of the cloning process that involves the following:a. Isolation of target DNA fragments (often referred to as inserts)b. Ligation of inserts into the plasmid, creating recombinant molecules c. Transformation of recombinant plasmids into bacteria or other suitable host for propagationd. Screening/selection of hosts containing the intended recombinant plasmid. For this stage(d), discuss the importance of a second marker that can be used for screening of genomic DNA for colonies containing the pka-1 under the principle of insertional inactivation. This should be properly explained using all the attributes of the plasmid described above.arrow_forward
- Which of the following processes can be used to clone animals? Select one: A. fusion of an adult cell's nucleus with an enucleated egg, followed by incubation in a surrogate B. separation of an early stage blastula into separate cells, followed by incubation in a surrogate C. use of mitochondrial DNA from adult female cells of another individual D. replication and dedifferentiation of adult stem cells from bone marrowarrow_forwardHow might the study of therapeutic cloning benefit scientific studies of reproductive cloning?arrow_forward1) If you wanted to create a clone of yourself, what would you donate_to start to the cloning process: a) one of your gametes or b) one of your cheek cells? (Pick one) 2) Please explain why you picked your choice of cells. A BI U SX2 x² 1. a) 2. 1.arrow_forward
- Give An example of positional cloning?arrow_forwardWoolly mammoths have been extinct for about 4,000 years, but we often find their well-preserved remains in Siberian permafrost. Research groups are now planning to use SCNT to resurrect these huge elephant-like mammals. No mammoth eggs have been recovered yet, so elephant eggs would be used instead. An elephant would also be the surrogate mother for the resulting embryo. The researchers may try a modified SCNT technique used to clone a mouse that had been dead and frozen for 16 years. Ice crystals that form during freezing break up cell membranes, so cells from the frozen mouse were in bad shape. Their DNA was transferred into donor mouse eggs, and cells from the resulting embryos were fused with undifferentiated mouse cells. Four healthy clones were born from the hybrid embryos. What are some of the pros and cons of cloning an extinct animal?arrow_forwardWhat is a fluorophore? If you wanted to fluorescently label a brain cell, describe one way you could genetically label a brain cell using a transgenic approach and give one way you could genetically label a brain cell using a gene targeting homologous recombination approach.arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
- Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSONBiology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStaxAnatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
- Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & CompanyLaboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education
![Text book image](https://www.bartleby.com/isbn_cover_images/9780134580999/9780134580999_smallCoverImage.gif)
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:PEARSON
![Text book image](https://www.bartleby.com/isbn_cover_images/9781947172517/9781947172517_coverImage_Textbooks.gif)
Biology 2e
Biology
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:OpenStax
![Text book image](https://www.bartleby.com/isbn_cover_images/9781259398629/9781259398629_smallCoverImage.gif)
Anatomy & Physiology
Biology
ISBN:9781259398629
Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:Mcgraw Hill Education,
![Text book image](https://www.bartleby.com/isbn_cover_images/9780815344322/9780815344322_smallCoverImage.gif)
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:9780815344322
Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:W. W. Norton & Company
![Text book image](https://www.bartleby.com/isbn_cover_images/9781260159363/9781260159363_smallCoverImage.gif)
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:9781260159363
Author:Martin, Terry R., Prentice-craver, Cynthia
Publisher:McGraw-Hill Publishing Co.
![Text book image](https://www.bartleby.com/isbn_cover_images/9781260231700/9781260231700_smallCoverImage.gif)
Inquiry Into Life (16th Edition)
Biology
ISBN:9781260231700
Author:Sylvia S. Mader, Michael Windelspecht
Publisher:McGraw Hill Education
Molecular Techniques: Basic Concepts; Author: Dr. A's Clinical Lab Videos;https://www.youtube.com/watch?v=7HFHZy8h6z0;License: Standard Youtube License