Molecular Cell Biology
Molecular Cell Biology
8th Edition
ISBN: 9781464183393
Author: Harvey Lodish, Arnold Berk, Chris A. Kaiser, Monty Krieger, Anthony Bretscher, Hidde Ploegh, Angelika Amon, Kelsey C. Martin
Publisher: W. H. Freeman
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Chapter 18, Problem 5RTC
Summary Introduction

To discuss:

The diseases that are treated by drugs that inhibit mitosis and bind to tubulin and microtubules and to find the mechanism that these drugs follow to alter the microtubule structure.

Introduction:

Microtubule is an anti-cancer drug. It helps in the treatment of cancer. Microtubule straightway polymerizes and depolymerizes. They go through two types of dynamics, instability and treadmilling. This is important in mitosis. Drugs may alter its polymerization dynamics which leads to cell death.

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