Human Anatomy
9th Edition
ISBN: 9780135168059
Author: Marieb, Elaine Nicpon, Brady, Patricia, Mallatt, Jon
Publisher: Pearson Education, Inc.,
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Chapter 18, Problem 4CRCAQ
Summary Introduction
To review:
The relationship between following observations: 5% of red blood cells were reticulocytes, the presence of polycythemia and a hematocrit of 65%.
Introduction:
Erythrocytes are also known as red blood cells (RBCs) and they serve as transporters of the respiratory gases in the human body. Erythrocytes are the most abundant cells in the human body. Red blood cells are the only class of blood cells that are not circular in shape and possess a biconcave disc shape.
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Hancock, a 65-year-old white male, was seen in triage with complaints of fatigue, malaise, anorexia, and hemoptysis of recent onset. A complete blood count (CBC) was ordered and revealed anemia and a shift to the left in granulocytes. Hematopoietic cells showed dysplastic features. Consider diagnostic probabilities and reflex testing that could provide differential diagnostic information.
The results of the CBC on Hancock were:
The neutrophilic cells show marked hyposegmentation and hypogranulation. Red blood cell (RBC) morphology includes anisocytosis and poikilocytosis, teardrop cells, ovalocytes, and schistocytes.
1- What features of the differential resemble chronic myeloid leukemia (CML)? What helps to distinguish this case from CML?
2- Which of the hematopoietic cell lines exhibit dyshematopoiesis in the bone marrow?
3- How would you classify the bone marrow cellularity? Why?
4- Identify at least two features of the bone marrow that are compatible with the diagnosis
5- What…
Xin’s blood was drawn and testing was conducted. His hematocrit was 45% and white-blood cell count was 2,500 white-blood cells/mm3, with the differential showing neutrophils 65%, lymphocytes 25%, monocytes 10%. A biopsy was taken of one of the discolored lesions and cell culture. After three days of growth the cells were confirmed as coming from malignant cancerous tissue. A magnetic resonance image (MRI) of the area around the skin lesions on Xin’s inner thigh revealed enlarged lymph nodes, a sign of potential metastasis. DNA sequencing of the lesion biopsy revealed DNA consistent with human herpesvirus 8, known as Kaposi’s sarcoma-associated herpesvirus, leading to the diagnosis of Kaposi’s sarcoma.
- What Disorders can be ruled in and out from this diagnosis?
In two complete sentences tell me the definition of a reticulocyte and why would we see an increase of them in the circulating blood
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Chapter 18 Solutions
Human Anatomy
Ch. 18 - Prob. 1CYUCh. 18 - Prob. 2CYUCh. 18 - Prob. 3CYUCh. 18 - Prob. 4CYUCh. 18 - What are the two components of Wright’s stain,...Ch. 18 - Prob. 6CYUCh. 18 - Prob. 7CYUCh. 18 - Prob. 8CYUCh. 18 - Prob. 9CYUCh. 18 - Prob. 10CYU
Ch. 18 - Prob. 11CYUCh. 18 - Prob. 1RQCh. 18 - Prob. 2RQCh. 18 - Prob. 3RQCh. 18 - Prob. 4RQCh. 18 - Prob. 5RQCh. 18 - Match the names of the blood cells in column B...Ch. 18 - In typically stained monocytes, the blue cytoplasm...Ch. 18 - Which class or classes of formed elements form the...Ch. 18 - Prob. 9RQCh. 18 - Prob. 10RQCh. 18 - Describe the structure of platelets, and explain...Ch. 18 - What is the difference between a hematopoietic...Ch. 18 - Prob. 13RQCh. 18 - Prob. 14RQCh. 18 - Prob. 15RQCh. 18 - Prob. 16RQCh. 18 - Prob. 17RQCh. 18 - Prob. 18RQCh. 18 - Prob. 19RQCh. 18 - Prob. 20RQCh. 18 - Prob. 21RQCh. 18 - Prob. 22RQCh. 18 - Prob. 1CRCAQCh. 18 - Prob. 2CRCAQCh. 18 - Prob. 3CRCAQCh. 18 - Prob. 4CRCAQCh. 18 - Prob. 5CRCAQCh. 18 - Your child has had a moderate fever for 2 days. On...Ch. 18 - Prob. 7CRCAQ
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