Anatomy & Physiology
Anatomy & Physiology
3rd Edition
ISBN: 9781259398629
Author: McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher: Mcgraw Hill Education,
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Chapter 17.5, Problem 13WDL
Summary Introduction

To determine:

The specific role of the protein kinase enzymes in the signal transduction pathway initiated by water-soluble hormones.

Introduction:

Water-soluble hormones such as proteins and biogenic amines are polar molecules that are incapable to diffuse in the plasma membrane. These molecules use alternative way for the stimulation of a target cell. These molecules cause stimulation, which initiates when the hormone interacts to a receptor present on the plasma membrane. Signal transduction pathway initiates when a water-soluble hormone binds to a receptor on the plasma membrane.

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Explain how a kinase cascade works. Why is this advantageous in the context of hormone signaling?
Activation of certain GPCRs triggers an intracellular signaling mechanism that involves activation of adenlyl cyclase and an increase of cAMP.  Which of the following statements best describes the the events that follow such a cAMP  increase? a.) The cAMP increase leads to activation of protein kinase C. b.) The cAMP increase leads to activation of the release of the gamma subunit from the GPCR. c.) The cAMP increase leads to activation of protein kinase A.
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Chapter 17 Solutions

Anatomy & Physiology

Ch. 17.3 - Prob. 6LOCh. 17.3 - Prob. 7LOCh. 17.3 - Identify which of the following hormone categories...Ch. 17.3 - What two events or processes associated with a...Ch. 17.3 - Prob. 8LOCh. 17.3 - Prob. 9LOCh. 17.3 - Prob. 1WDTCh. 17.3 - Prob. 8WDLCh. 17.4 - Prob. 10LOCh. 17.4 - Why are carrier proteins necessary for...Ch. 17.4 - What is the added benefit of a carrier protein?Ch. 17.4 - Prob. 11LOCh. 17.4 - Prob. 12LOCh. 17.4 - Prob. 2WDTCh. 17.4 - What is the relationship of hormone synthesis to...Ch. 17.5 - Prob. 13LOCh. 17.5 - Where are lipid-soluble hormone receptors located?...Ch. 17.5 - Prob. 14LOCh. 17.5 - Prob. 13WDLCh. 17.6 - Prob. 15LOCh. 17.6 - Prob. 16LOCh. 17.6 - Prob. 3WDTCh. 17.6 - How does down-regulation of cellular receptors...Ch. 17.6 - Prob. 17LOCh. 17.6 - What effects are seen when hormones act...Ch. 17.7 - Prob. 18LOCh. 17.7 - Prob. 19LOCh. 17.7 - What is the anatomic connection between the...Ch. 17.7 - Prob. 20LOCh. 17.7 - Prob. 4WDTCh. 17.7 - Prob. 17WDLCh. 17.7 - Prob. 21LOCh. 17.7 - Prob. 22LOCh. 17.7 - Prob. 18WDLCh. 17.7 - Prob. 23LOCh. 17.7 - Prob. 24LOCh. 17.7 - Prob. 5WDTCh. 17.7 - Prob. 19WDLCh. 17.7 - Prob. 20WDLCh. 17.8 - Prob. 25LOCh. 17.8 - Prob. 26LOCh. 17.8 - Prob. 6WDTCh. 17.8 - Prob. 21WDLCh. 17.8 - Prob. 27LOCh. 17.8 - Prob. 7WDTCh. 17.8 - What is the relationship of TRH, TSH, and TH in...Ch. 17.8 - What are the primary target organs/issues of TH?...Ch. 17.8 - Prob. 28LOCh. 17.9 - Prob. 24WDLCh. 17.9 - Prob. 29LOCh. 17.9 - Prob. 30LOCh. 17.9 - Prob. 25WDLCh. 17.9 - LEARNING OBJECTIVE 31. Describe the homeostatic...Ch. 17.9 - Prob. 26WDLCh. 17.9 - What are the primary target organs/tissues of...Ch. 17.10 - Prob. 32LOCh. 17.10 - Prob. 33LOCh. 17.10 - Why is the pancreas considered both an exocrine...Ch. 17.10 - Prob. 34LOCh. 17.10 - Prob. 35LOCh. 17.10 - Prob. 8WDTCh. 17.10 - Is the stimulus for insulin and glucagon release...Ch. 17.10 - What is the stimulus, receptor, control center,...Ch. 17.10 - Which of these hormones causes release of glucose...Ch. 17.11 - LEARNING OBJECTIVE 36. Describe the general...Ch. 17.11 - How do melatonin levels change throughout the day?Ch. 17.11 - LEARNING OBJECTIVE 37. Describe the general...Ch. 17.11 - What is the primary hormone released from the...Ch. 17.11 - Prob. 38LOCh. 17.11 - Prob. 34WDLCh. 17.11 - Prob. 35WDLCh. 17.12 - Prob. 39LOCh. 17.12 - What general changes occur to the ability of...Ch. 17 - Prob. 1DYBCh. 17 - This hormones primary function is to regulate...Ch. 17 - Which of the following are components of...Ch. 17 - A hormone released from the anterior pituitary is...Ch. 17 - Prob. 5DYBCh. 17 - Prob. 6DYBCh. 17 - Glucagon has an __________ effect to insulin on...Ch. 17 - Glucocorticoids (e.g., cortisol) are produced in...Ch. 17 - Prob. 9DYBCh. 17 - All of the following hormones are released from...Ch. 17 - Prob. 11DYBCh. 17 - Prob. 12DYBCh. 17 - Explain the three mechanisms used to stimulate...Ch. 17 - Identify the three chemical classes of hormones,...Ch. 17 - Describe how local hormones differ from...Ch. 17 - Explain the function of carrier proteins in...Ch. 17 - Describe how water-soluble hormones interact with...Ch. 17 - Explain how the hypothalamus oversees and controls...Ch. 17 - Explain how the hypothalamus oversees and controls...Ch. 17 - Discuss the homeostatic system involving insulin.Ch. 17 - George is a 43-year-old construction worker who...Ch. 17 - What is the best diagnostic test to determine if...Ch. 17 - Jelena is late for work and is rushing to get out...Ch. 17 - Blood samples from a young woman named Michelle...Ch. 17 - Stephen is taking a new weight-loss supplement...Ch. 17 - Prob. 1CSLCh. 17 - Prob. 2CSLCh. 17 - Henry is a well-informed patient who is interested...
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