To draw: The structure of reaction product catalyzed by mutated isocitrate dehydrogenase. Concept introduction: Isocitrate dehydrogenase is an important enzyme of the citric acid cycle. It catalyzes the reaction of isocitrate to α-ketoglutarate. In human brain cancer, isocitrate dehydrogenase has its mutated form and catalyzes the NADP+- dependent reduction of the carbonyl group of α-ketoglutarate.

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Answer 1

Question

Chapter 17, Problem 9E

Summary Introduction

To draw: The structure of reaction product catalyzed by mutated isocitrate dehydrogenase.

Concept introduction: Isocitrate dehydrogenase is an important enzyme of the citric acid cycle. It catalyzes the reaction of isocitrate to α-ketoglutarate. In human brain cancer, isocitrate dehydrogenase has its mutated form and catalyzes the NADP+- dependent reduction of the carbonyl group of α-ketoglutarate.

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Answer 2

Question

Chapter 17, Problem 9E

Summary Introduction

To draw: The structure of reaction product catalyzed by mutated isocitrate dehydrogenase.

Concept introduction: Isocitrate dehydrogenase is an important enzyme of the citric acid cycle. It catalyzes the reaction of isocitrate to α-ketoglutarate. In human brain cancer, isocitrate dehydrogenase has its mutated form and catalyzes the NADP+- dependent reduction of the carbonyl group of α-ketoglutarate.

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Answer 3

Question

Chapter 17, Problem 9E

Summary Introduction

To draw: The structure of reaction product catalyzed by mutated isocitrate dehydrogenase.

Concept introduction: Isocitrate dehydrogenase is an important enzyme of the citric acid cycle. It catalyzes the reaction of isocitrate to α-ketoglutarate. In human brain cancer, isocitrate dehydrogenase has its mutated form and catalyzes the NADP+- dependent reduction of the carbonyl group of α-ketoglutarate.

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Answer 4

Question

Chapter 17, Problem 9E

Summary Introduction

To draw: The structure of reaction product catalyzed by mutated isocitrate dehydrogenase.

Concept introduction: Isocitrate dehydrogenase is an important enzyme of the citric acid cycle. It catalyzes the reaction of isocitrate to α-ketoglutarate. In human brain cancer, isocitrate dehydrogenase has its mutated form and catalyzes the NADP+- dependent reduction of the carbonyl group of α-ketoglutarate.

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Answer 5

Chapter 17, Problem 9E

Summary Introduction

To draw: The structure of reaction product catalyzed by mutated isocitrate dehydrogenase.

Concept introduction: Isocitrate dehydrogenase is an important enzyme of the citric acid cycle. It catalyzes the reaction of isocitrate to α-ketoglutarate. In human brain cancer, isocitrate dehydrogenase has its mutated form and catalyzes the NADP+- dependent reduction of the carbonyl group of α-ketoglutarate.

Answer 6

Chapter 17, Problem 9E

Summary Introduction

To draw: The structure of reaction product catalyzed by mutated isocitrate dehydrogenase.

Concept introduction: Isocitrate dehydrogenase is an important enzyme of the citric acid cycle. It catalyzes the reaction of isocitrate to α-ketoglutarate. In human brain cancer, isocitrate dehydrogenase has its mutated form and catalyzes the NADP+- dependent reduction of the carbonyl group of α-ketoglutarate.

Answer 7

Chapter 17, Problem 9E

Summary Introduction

To draw: The structure of reaction product catalyzed by mutated isocitrate dehydrogenase.

Concept introduction: Isocitrate dehydrogenase is an important enzyme of the citric acid cycle. It catalyzes the reaction of isocitrate to α-ketoglutarate. In human brain cancer, isocitrate dehydrogenase has its mutated form and catalyzes the NADP+- dependent reduction of the carbonyl group of α-ketoglutarate.

Answer 8

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Answer 9

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Answer 11

Ch. 17 - Prob. 1E Ch. 17 - 2. If acetyl-CoA is labeled with l4C at its methyl...Ch. 17 - 3. List four possible metabolic fates for pyruvate...Ch. 17 - 4. Explain why metabolic acidosis (Box 2-2) may...Ch. 17 - 5. Which one of the live steps of the pyruvate...Ch. 17 - Prob. 6E Ch. 17 - 7. Photosynthetic organisms use elaborate...Ch. 17 - 6. Does the pyruvate-formate lyase reaction...Ch. 17 - Prob. 9E Ch. 17 - Prob. 10E

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