Chapter 17, Problem 5RTC

Summary Introduction

To write:

The conversion of the nucleotide state is due to the actin subunits assembly and disassembly. The result for the actin filament assembly/disassembly due to a mutation that prevents the actin-binding ability to ATP. The consequence of a mutation which prevents the ability of actin to hydrolyze the ATP molecule.

Introduction:

Actin protein belongs to a family of globular and multi-functional proteins. These proteins forms microfilaments. Basically, it is present in all the eukaryotic cells (except in nematode sperm). Actin is a spherical protein which forms the thin filament in the muscle cells. Thin filaments are made up of two long chains of actin molecules. These two actin chains are twisted around each other. Each of the actin molecules bears a myosin-binding location on which a myosin head can attach or bind.