Microbiology with Diseases by Body System (5th Edition)
5th Edition
ISBN: 9780134477206
Author: Robert W. Bauman Ph.D.
Publisher: PEARSON
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Chapter 17, Problem 2TMW
A diagnostician used an ELISA to show that a newborn had antibodies against HIV in her blood. However, six months later, the same test was negative. How can this be?
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To diagnose someone with HIV, what do they look for in the blood?
You have a patient who has been injured by a rusty nail. As a precaution, you vaccinate her against tetanus.
In response to the vaccine, how does her body produce antibodies against C. tetani and prevent future illness due to tetanus?
A)B cells that produce an appropriate antibody undergo genomic rearrangement in order to produce other cells that secrete the same antibody.
B)Every cell in her immune system produces antibodies against C. tetani.
C)B cells with an appropriate antibody are stimulated to divide, producing plasma cells that make antibodies to C. tetani, and memory cells that "remember" C. tetani.
D)Every B cell in her body produces antibodies against C. tetani.
To diagnosis, we used a procedure known as a "sandwich ELISA" (Enzyme-Linked Immunosorbent Assay).
1.In the "ELISA sandwich," what is the "meat"?
2.Both patients A and B had positive results. Why are these two patients' outcomes so different?
3.What is one potential cause of an ELISA false negative result? What is one potential cause of an ELISA false positive result? What is another example of how an ELISA assay should be used?
Chapter 17 Solutions
Microbiology with Diseases by Body System (5th Edition)
Ch. 17 - Prob. 1TMWCh. 17 - A diagnostician used an ELISA to show that a...Ch. 17 - To obtain immediate immunity against tetanus, a...Ch. 17 - Which of the following vaccine types is commonly...Ch. 17 - Prob. 3MCCh. 17 - When antigen and antibodies combine, maximal...Ch. 17 - An anti-antibody is used when _________. a. an...Ch. 17 - Prob. 6MCCh. 17 - Prob. 7MCCh. 17 - Prob. 8MC
Ch. 17 - Prob. 9MCCh. 17 - Prob. 10MCCh. 17 - Prob. 11MCCh. 17 - An antiserum is ________. a. an anti-antibody b....Ch. 17 - Prob. 13MCCh. 17 - Prob. 14MCCh. 17 - Prob. 15MCCh. 17 - Prob. 1MTFCh. 17 - Prob. 2MTFCh. 17 - Prob. 3MTFCh. 17 - Modified True/False 4. _________________ ELISA is...Ch. 17 - Prob. 5MTFCh. 17 - Match the characteristic in the first column with...Ch. 17 - Identify the chemicals represented by this artists...Ch. 17 - Prob. 2VICh. 17 - Compare and contrast the Chinese practice of...Ch. 17 - What are the advantages and disadvantages of...Ch. 17 - Compare the advantages and disadvantages of...Ch. 17 - How does precipitation differ from agglutination?Ch. 17 - Explain how a pregnancy test works at the...Ch. 17 - Compare and contrast herd immunity and contact...Ch. 17 - How does nephelometry differ from turbidimetry?Ch. 17 - Is it ethical to approve the use of a vaccine that...Ch. 17 - Which is worse: to use a diagnostic test for HIV...Ch. 17 - Discuss the importance of costs and technical...Ch. 17 - What bodily fluids, in addition to blood serum,...Ch. 17 - Why might a serological test give a false positive...Ch. 17 - Some researchers want to distinguish B cells from...Ch. 17 - Describe three ways by which genetic recombinant...Ch. 17 - How does a toxoid vaccine differ from an...Ch. 17 - Explain why many health organizations promote...Ch. 17 - Contrast a hemagglutination test with a viral...Ch. 17 - Prob. 11CTCh. 17 - Draw a picture showing, at both the molecular and...Ch. 17 - Using the following terms, fill in the following...
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