Genetics: Analysis and Principles
5th Edition
ISBN: 9780073525341
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Chapter 16.3, Problem 1COMQ
When mice carrying the
allele exhibit a darker coat, this
a. a greater level of DNA methylation and a decrease in the expression of the Agouti gene.
b. a lower level of DNA methylation and a decrease in the expression of the Agouti gene.
c. a greater level of DNA methylation and the overexpression of the Agouti gene.
d. a lower level of DNA methylation and the overexpression of the Agouti gene.
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When mice carrying the Avy allele exhibit a darker coat, thisphenotype is thought to be caused by dietary factors thatresult ina. a greater level of DNA methylation and a decrease in theexpression of the Agouti gene.b. a lower level of DNA methylation and a decrease in theexpressionof the Agouti gene.c. a greater level of DNA methylation and the overexpressionof the Agouti gene.d. a lower level of DNA methylation and the overexpression ofthe Agouti gene.
The expression of antigen A or antigen B in red blood cells requires the help of an H antigen. A recessive mutation (h) that prevents the synthesis of the H antigen also prevents the expression of A and B antigens. This is called the Bombay effect. There is no ill effect in an individual with this mutation, but complications with blood transfusions or parental disputes may arise.
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Select one:
a. multiple alleles
b. epistasis
c. genomic imprinting
d. altered methylation
Chapter 16 Solutions
Genetics: Analysis and Principles
Ch. 16.1 - Which of the following are examples of molecular...Ch. 16.1 - 2. An epigenetic modification to a specific gene...Ch. 16.1 - Prob. 3COMQCh. 16.1 - Epigenetic changes may a. be programmed during...Ch. 16.2 - 1. For the Igf2 gene, where do de novo methylation...Ch. 16.2 - 2. For XCI to occur, where are the Xist and Tsix...Ch. 16.2 - 3. Which of the following possibilities could...Ch. 16.3 - 1. When mice carrying theallele exhibit a darker...Ch. 16.3 - Which of the following types of epigenetic changes...Ch. 16.4 - Prob. 1COMQ
Ch. 16.4 - Prob. 2COMQCh. 16.4 - Prob. 3COMQCh. 16.4 - Prob. 4COMQCh. 16 - Prob. 1CONQCh. 16 - List and briefly describe five types of molecular...Ch. 16 - Prob. 3CONQCh. 16 - What is the key difference between cis and...Ch. 16 - Prob. 6CONQCh. 16 - Prob. 7CONQCh. 16 - 7. Outline the molecular steps in the process of...Ch. 16 - Prob. 9CONQCh. 16 - 9. In general, explain how epigenetic...Ch. 16 - 10. What are the contrasting roles of trithorax...Ch. 16 - Describe the molecular steps by which polycomb...Ch. 16 - Prob. 13CONQCh. 16 - Using coat color in mice and the development of...Ch. 16 - How can environmental agents that do not cause...Ch. 16 - Prob. 5CONQCh. 16 - Define alternative splicing. What are advantages...Ch. 16 - What is the function of a splicing factor? Explain...Ch. 16 - Figure 16.8 shows the products of alternative...Ch. 16 - Lets suppose a person is homozygous for a mutation...Ch. 16 - Prob. 20CONQCh. 16 - What are the advantages and disadvantages of mRNAs...Ch. 16 - Prob. 22CONQCh. 16 - Prob. 23CONQCh. 16 - Prob. 24CONQCh. 16 - Describe how the binding of the iron regulatory...Ch. 16 - Prob. 1EQCh. 16 - In the experiments described in Figure 16.8,...Ch. 16 - Prob. 3EQCh. 16 - A research study indicated that an agent in...Ch. 16 - Lets suppose you were interested in developing...Ch. 16 - E6. In Experiment 16A by Fire and Mello, were they...Ch. 16 - E7. Explain how the data of Fire and Mello...Ch. 16 - Prob. 8EQCh. 16 - 2. Discuss the similarities and differences of...Ch. 16 - How are regulatory transcription factors...
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- Which of the following scenarios best describes an epistatic gene? Select one: a. Fur pattern is controlled by two genes such that one gene inhibits the expression of the other gene. b. Chicken combs follow a dominance hierarchy whereby a walnut comb is the most dominant and a single comb is the least dominant. c. Individuals with sickle cell anemia and carriers of the sickle cell allele have some resistance to malaria. d. Mouse fur colours are expressed as a blend of the dominant black colour and the recessive white colour, resulting in a heterozygous brown colour.arrow_forwardIn mammals, males have X and Y sex chromosomes, while females have two Xs. While the Y sex chromosome has very few genes associated with it, the X sex chromosome has many that are important to maintain life. How do mammals account for this in terms of equaling out gene expression levels? A. Mammals do not need to account for this, but birds do. B. Females produce more proteins from X-linked genes than males do. C. The single X of the males works twice as hard to keep up with the female’s two Xs. D. The females have one X inactivated to permit the males to keep pace with them.arrow_forwardWhich of the following statements does NOT describe an environmental influence on the expression of a gene? Select one: a. Siamese cats have darkened paws, nose, and tip of tail due to a gene that allows their skin and fur to darken in the parts of their bodies that need to retain more heat, their extremities. b. More than a single gene is involved in the expression of human height, weight, and skin colour. c. Exposure to sunlight increases melanin production in human skin. d. Colder incubation temperatures of gecko eggs yield more females and warmer temperatures yield more males.arrow_forward
- DNA methylation prevents gene expression. Methylation and de-methylation are stimulated by a variety of environmental factors. Methylation patterns in DNA can be passed onto daughter cells including eggs and sperm. An implication of these facts is that Group of answer choices A. methylation is rare B. fewer and fewer genes will be expressed each generation C. more genes will be expressed in offspring than in their parents D. old individuals will express fewer genes than young individuals E. environmental effects on individuals can have effects on their offspringarrow_forwardFor the Igf2 gene, where do de novo methylation and maintenancemethylation occur?a. De novo methylation occurs in sperm, and maintenancemethylation occurs in egg cells.b. De novo methylation occurs in egg cells, and maintenancemethylation occurs in sperm cells.c. De novo methylation occurs in sperm, and maintenancemethylation occurs in somatic cells of offspring.d. De novo methylation occurs in egg cells, and maintenancemethylation occurs in somatic cells of offspring.arrow_forwardWhich pathology leads to an increased risk of Alzheimer’s disease? Select one: a. Accumulation of the Amyloid β peptide b. Homozygosity for the e2 ApoE allele c. Sedentary lifestyle in young adulthood d. A mutation in the presenilin 4 gene e. Increase in blood cholesterolarrow_forward
- D An epistatic gene A is a gene that is A at a different location than gene B and that is capable of suppressing gene B B) very close to gene B and thus they will be passed together to the offspring at the same location as gene B and thus their expression is similar far from gene B and can increase the expression of gene Barrow_forwardIn organisms with X and Y chromosomes, many more genes can be found on the X chromosome than on the Y chromosome. In mammals, how might this deviate from traits being expressed, according to Mendel? A. Females might exhibit a mix of traits rather than all dominant or all recessive traits. B. Only females will have the traits resulting from the X-linked genes. C. Females will overproduce some proteins in relation to males’ production levels. D. This will not result in individuals deviating from Mendel’s principles.arrow_forwardWhich of the following statements describes an example of a phenocopy? Explain your reasoning. a. Phenylketonuria results from a recessive mutation that causes light skin as well as intellectual disability. b. Human height is influenced by genes at many different loci. c. Dwarf plants and mottled leaves in tomatoes are caused by separate genes that are linked. d. Vestigial wings in Drosophila are produced by a recessive mutation. This trait is also produced by high temperature during development. e. Intelligence in humans is influenced by both genetic and environmental factors.arrow_forward
- If a Drosophila female that is homozygous for an X-linked recessive mutation is bred with a male that carries the corresponding wild-type allele, the offspring will..... a. show the mutant phenotype in all individuals. b. be uniform wild-type. c. show a phenotype intermediate to the parents' phenotype. d. show the mutant phenotype in all males and the wild-type phenotype in all females. e. have mutant and wild-type males and mutant and wild-type females.arrow_forwardF1 mice targeted using CRISPR/Cas9 and an HDR DNA fragment is the first choice when modeling a. Autosomal dominant disorders due to missense mutations b. Autosomal recessive disorders due to knockout mutations C. Autosomal dominant disorders due to haploinsufficiency d. X-linked recessive disorders in females e. Autosomal recessive disorders due to missense mutationsarrow_forwardThis data shows the efficacy of different treatments on the survival rates of patients with glioblastomas, as well as methylated, and on methylated MGMT promoters. A. Explain the trends in the figure B. Relate MGMT methylation to the central dogma/flow of genetic information, and how genes are expressed. arrow_forward
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