Biology: Life on Earth with Physiology Plus Mastering Biology with Pearson eText -- Access Card Package (11th Edition)
Biology: Life on Earth with Physiology Plus Mastering Biology with Pearson eText -- Access Card Package (11th Edition)
11th Edition
ISBN: 9780133910605
Author: Gerald Audesirk, Teresa Audesirk, Bruce E. Byers
Publisher: PEARSON
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Chapter 14, Problem 1MC
Summary Introduction

Introduction:

Single nucleotide polymorphism is caused by the change of an amino acid at a single position in the amino acid chain of the protein. It causes a change in the structure, conformation and molecular function of the protein.

Expert Solution & Answer
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Answer to Problem 1MC

Correct answer:

Translocation causes a change in the location of the gene on the chromosome locus whereas single nucleotide polymorphism is caused due to change of an amino acid at a single position in the polypeptide chain. Therefore, option (a) is correct.

Option (a) is given as “It is usually caused by a translocation mutation”.

Explanation of Solution

Justify reasons for the correct statement:

Single nucleotide polymorphism changes the structure, function and molecular mechanism of the protein due to an alteration of an amino-acid at a single position on the polypeptide chain.

Hence, option (a) is correct.

Justify reasons for the incorrect statements:

Option (b) is given as “It is usually caused by a nucleotide substitution mutation”. This mutation causes a change in the amino acid present at a specific position in the polypeptide leading to a change in the functioning mechanism of the protein. Hence, it is a wrong answer.

Option (c) is given as “It may change the phenotype of an organism”. The phenotype of an organism is changed due to change in the sequence of the nucleotide of the genes present on chromosomes. Hence, it is a wrong answer.

Option (d) is given as “It is inherited from parent to offspring”. Genes are inherited from parent to offspring. Hence, it is a wrong answer.

Hence, options (b), (c), and (d) are incorrect.

Conclusion

The statement which is not true regarding the single nucleotide polymorphism is that it is usually caused by a translocation mutation. Translocation mutation is caused due to the change in the chromosome locus of the gene under study whereas the single nucleotide polymorphism is caused due to the alteration and replacement of an amino-acid at a specific position of the polypeptide chain.

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Students have asked these similar questions
Which of the following statements best describes the outcome of a mutation?   a. A mutation always results in a mutant genotype   b. A mutation always results in a mutant karyotype   c. A mutation always results in a mutant phenotype   d. A mutation always results in a mutant protein
A mutation in a coding region of DNA, but that does not change the amino acid, would almostcertainly be considered a(n) ____________ allele.And this kind of mutation is also called ___________ .b. Most nonsense mutations would create __________ alleles.However, describe a situation in which a nonsense mutation would create an isomoprh allele.c. A missense mutation will usually create a(n) _________ allele.However, describe a situation in which a missense mutation would create a neomorph allele.
In general, all mutations can be considered harmful, because most genetic systems are already optimized to work correctly and efficiently.  A. True b. False; mutations are considered harmful only if they have a direct effect on the ability of cells to synthesize DNA c. False; some mutations are harmful, and some are considered beneficial

Chapter 14 Solutions

Biology: Life on Earth with Physiology Plus Mastering Biology with Pearson eText -- Access Card Package (11th Edition)

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Mitochondrial mutations; Author: Useful Genetics;https://www.youtube.com/watch?v=GvgXe-3RJeU;License: CC-BY