Molecular Cell Biology
Molecular Cell Biology
8th Edition
ISBN: 9781464183393
Author: Harvey Lodish, Arnold Berk, Chris A. Kaiser, Monty Krieger, Anthony Bretscher, Hidde Ploegh, Angelika Amon, Kelsey C. Martin
Publisher: W. H. Freeman
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Chapter 13, Problem 14RTC
Summary Introduction

To write:

About the role of Ran-GAP and Ran-GEF for the unidirectional transportation of the cargo proteins molecules having a nuclear export signal (NES).

Introduction:

Ran is RAs-related Nuclear protein which is also known as a GTP-binding nuclear protein. It is a protein which is encoded by the RAN gene in humans. Ran-GAP is a protein which is involved in the passage of other proteins to the nucleus from the cytoplasm in eukaryotic cells. It is this ran gradient that offers the required energy for the transport of the protein inside and outside of the nucleus. It is commonly done by the karyopherin proteins.

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Biomolecules - Protein - Amino acids; Author: Tutorials Point (India) Ltd.;https://www.youtube.com/watch?v=ySNVPDHJ0ek;License: Standard YouTube License, CC-BY