Biology
Biology
4th Edition
ISBN: 9781259188121
Author: Peter Stiling, Robert Brooker, Linda Graham, Eric Widmaier
Publisher: McGraw-Hill Education
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Chapter 12, Problem 1TY

Which of the following best represents the central dogma of gene expression?

  1. a. During transcription, DNA codes for polypeptides.
  2. b. During transcription, DNA codes for mRNA, which codes for polypeptides during translation.
  3. c. During translation, DNA codes for mRNA, which codes for polypeptides during transcription.
  4. d. none of the above
Expert Solution & Answer
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Summary Introduction

Introduction: The central dogma represents the core of gene expression. The gene is made up of DNA and the information stored in the particular segments of DNA impacts cell and organs. Central dogma gives away the direction of the expression and the flow of information.

Answer to Problem 1TY

Correct answer: The best description of a central dogma according to the expression of the gene is “during transcription, DNA codes for mRNA, which codes for polypeptides during translation”. Hence, the correct answer is option b.

Explanation of Solution

Reason for correct answer:

Gene is made up of the DNA and the information stored in the gene cannot be directly changed into protein. According to the central dogma, the DNA of the gene helps in the formation of mRNA by transcription. Translation of the mRNA sequence helps in the synthesis of a protein.

Option b. is given as “During transcription, DNA codes for mRNA, which codes for polypeptides during translation.”

The central dogma represents transcription of a gene followed by translation to be the sequence for gene expression. Hence, the correct answer is option b.

Reasons for incorrect answer:

Option a. is given as, “During transcription, DNA codes for polypeptides”.

The transcription involves the formation of mRNA from DNA. It does not involve DNA to directly code for polypeptides. Hence, option a. is incorrect.

Option c. is given as, “During translation DNA codes for mRNA, which codes for polypeptides during transcription”.

The process of synthesis of mRNA from DNA is called transcription. Translation of the mRNA sequence helps in the synthesis of a protein. Hence, option c. is incorrect.

Option d. is given as, “none of the above”.

The given option b describes the correct expression of the central dogma of gene expression. Hence, option d. is incorrect.

Hence, the options a., c., and d. are incorrect.

Conclusion

Hence central dogma states that the DNA of the gene helps in the formation of mRNA by transcription, and translation of the mRNA sequence helps in the synthesis of protein.

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Students have asked these similar questions
there is the statement: "Both stem cells and specialized cells have all the same genes.  They differ in the regulation of those genes and express very different sets of genes ". Which one of the following explanations best accounts for this difference in stem cell and specialized cell gene expression?     A. Stem cells and specialized cells have different activators and repressors that affect transcription   B. Stem cells and specialized cells have different promoter sequences for their genes,  thus affecting transcription   C. Stem cells and specialized cells have different ribosomes that affect translation   D. Stem cells and specialized cells use different start codons on mRNAs, thus affecting translation
Which of the following is true for both prokaryotic and eukaryotic gene expression? A. After transcription, a 3' poly-A tail and a 5' cap are added to MRNA. B. Translation of MRNA can begin before transcription is complete. C. RNA polymerase binds to the promoter region to begin transcription. D. MRNA is synthesized in the 3' → 5' direction.
Arrange the statements in their proper order by writing the corresponding letter (e.g. A) for each statement in the space provided below. A. The single-stranded RNA would complement the target RNA. B. Gene expression is inactivated once the mRNA is no longer accessible for translation. C. The risk-induced silencing complex which is composed of RNA and protein subunits is formed. D. Double-stranded, non-coding RNA is cleaved by Dicer. E. The mRNA can be cleaved or remain bound by the RISC. 1. 2. 3. 4. 5.
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