Biology
4th Edition
ISBN: 9781259188121
Author: Peter Stiling, Robert Brooker, Linda Graham, Eric Widmaier
Publisher: McGraw-Hill Education
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Chapter 11.4, Problem 4CC
Summary Introduction
To determine: The requirement that telomerase uses as a template to make the DNA repeat sequence.
Introduction: Telomerase is an enzyme that was discovered by Elizabeth Blackburn. It is an enzyme involved in the production of telomere in the human body. Telomeres are the protecting units of chromosomes in eukaryotes. They are repeating DNA sequences and contain a 3ʹoverhang at its 3ʹterminal. It has been discovered that protein and RNA are important components of a telomerase enzyme.
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Macmillan Learning
What factors promote the fidelity of replication during synthesis of the leading strand of DNA?
removal of the RNA primers between Okazaki fragments by DNA polymerase I
breaks that occur in the leading strand are repaired by DNA ligase
prevention of mismatched nucleotides at the replication fork by topoisomerase
removal of wrongly inserted nucleotides by the 3'-exonuclease activity of DNA polymerase III
Watson-Crick base pairing between the template and leading strand
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Chapter 11 Solutions
Biology
Ch. 11.1 - Prob. 1BCCh. 11.1 - Prob. 1EQCh. 11.1 - Prob. 2EQCh. 11.1 - CoreSKILL In the experiment of Avery, MacLeod,...Ch. 11.2 - Prob. 1CCCh. 11.2 - Prob. 2CCCh. 11.2 - Prob. 3CCCh. 11.2 - Prob. 4CCCh. 11.3 - If this experiment was conducted for four rounds...Ch. 11.4 - Molecular Mechanism of DNA Replication Concept...
Ch. 11.4 - Prob. 2CCCh. 11.4 - Prob. 3CCCh. 11.4 - Prob. 4CCCh. 11.5 - Prob. 1CCCh. 11.5 - Prob. 2CCCh. 11.5 - Prob. 1BCCh. 11 - Why did researchers initially believe that the...Ch. 11 - Prob. 2TYCh. 11 - Which of the following equations is accurate...Ch. 11 - Prob. 4TYCh. 11 - Which of the following statements about the...Ch. 11 - Meselson and Stahl were able to demonstrate...Ch. 11 - During replication of a DNA molecule, the daughter...Ch. 11 - Prob. 8TYCh. 11 - A nucleosome is a. a dark-staining body composed...Ch. 11 - The conversion of euchromatin into heterochromatin...Ch. 11 - What are the four key criteria that the genetic...Ch. 11 - A double-stranded DNA molecule contains 560...Ch. 11 - Prob. 3CQCh. 11 - Prob. 1COQCh. 11 - CoreSKILL How might you provide evidence that DNA...
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- Human Genome Replication Rate Assume DNA replication proceeds at a rate of 100 base pairs per second in human cells and origins of replication occur every 300 kbp. Assume also that human DNA polymerases are highly processive and only two molecules of DNA polymerase arc needed per replication fork. How long would it take to replicate the entire diploid human genome? How many molecules of DNA polymerase does each cell need to carry out this task?arrow_forwardCorrect order ib which the following enzynes would operate to fix a damaged nucleotide in a human gene. a) nuclease, DNA polymerase, RNA primase b) helicase, DNA polymerase, DNA ligase c) DNA ligase, nuclease, helicase d) nuclease, DNA polymerase, DNA ligasearrow_forwardExplain well please, asaparrow_forward
- Question. What would the forward primer sequence look like if it were intended to bind the area of the DNA template?arrow_forwardReplication:- what other enzymes are involved in the initiation phase?- explain the role of primers in this phase- how is the building of the leading strand different from that of the lagging strand?arrow_forwardPlease ASAP. Thank uarrow_forward
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