Human Physiology: An Integrated Approach (8th Edition)
8th Edition
ISBN: 9780134605197
Author: Dee Unglaub Silverthorn
Publisher: PEARSON
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Chapter 11, Problem 6RQ
List four things that can happen to autonomic neurotransmitters after they are released into a synapse.
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List four things that can happen to autonomic neurotransmitters after they are released into a
synapse.
Besides the standard post- and pre-synapse that exchange information, non neuronal cell types also play a role in synaptic transmission. One of those are called astrocytes and can form a tripartite synapse. Explain the roles of astrocytes in synaptic transmission.
Depression is a condition in which sufferers may feel low mood, lack of motivation and sleep. It is caused by a lack of serotonin in the synaptic cleft of neurone pathways. Serotonin is a neurotransmitter.
a) Describe how serotonin acts as a neurotransmitter. Using your understanding of synaptic transmission, explain how communication between neurones in serotonin pathways of the brain would be affected in someone with depression.
b) Doctors use tubocurarine drug as an anaesthetic as it temporarily paralyses muscles. It blocks receptors at neuromuscular junctions. Why does this lead to paralysis?
Chapter 11 Solutions
Human Physiology: An Integrated Approach (8th Edition)
Ch. 11.1 - Prob. 1CCCh. 11.1 - The central nervous system consists of the...Ch. 11.1 - Prob. 3CCCh. 11.1 - A nerve that carries both sensory and motor...Ch. 11.1 - Prob. 5CCCh. 11.1 - In what organelle is most intracellular Ca2+...Ch. 11.1 - Prob. 7CCCh. 11.1 - Prob. 8CCCh. 11.1 - Prob. 9CCCh. 11.2 - Prob. 10CC
Ch. 11.2 - Compare gating and ion selectivity of...Ch. 11.2 - Prob. 12CCCh. 11 - Prob. 1RQCh. 11 - Prob. 2RQCh. 11 - Prob. 3RQCh. 11 - Prob. 4RQCh. 11 - Neurons that secrete acetylcholine are described...Ch. 11 - List four things that can happen to autonomic...Ch. 11 - Prob. 7RQCh. 11 - Prob. 8RQCh. 11 - Somatic motor pathways a. are excitatory or...Ch. 11 - Prob. 10RQCh. 11 - Prob. 11RQCh. 11 - Compare and contrast: a. neuroeffector junctions...Ch. 11 - Prob. 13RQCh. 11 - Create a concept map comparing the somatic motor...Ch. 11 - If a target cells receptor is _______ (use items...Ch. 11 - Ganglia contain the cell bodies of (choose all...Ch. 11 - Prob. 17RQCh. 11 - You have discovered a neuron that innervates an...Ch. 11 - Prob. 19RQCh. 11 - Prob. 20RQ
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- What are the criteria for identification of the neurotransmitter at a particular synapse? Which two criteria are sufficient to conclude that a candidate substance is a neurotransmitter?arrow_forwardAs dopamine neurotransmitters are also responsible for producing feelings of euphoria (pleasure), many people affected with Parkinson's disease suffer from depression. A common treatment for Parkinson's is Levodopa, a chemical that turns into dopamine when it passes into the brain. From what you have learned about synapses, explain if people being treated with Levodopa for Parkinson's symptoms would require additional treatment for depression?arrow_forwardlist at least eight ways in which the effectiveness of synapses may be altered and explain each pointarrow_forward
- The following steps refer to various stages in transmission at a chemical synapse. 1. Neurotransmitter binds with receptors associated with the postsynaptic membrane. 2. Calcium ions rush into neuron's cytoplasm. 3. An action potential depolarizes the membrane of the presynaptic axon terminal. 4. The ligand-gated ion channels open. 5. The synaptic vesicles release neurotransmitter into the synaptic cleft. Which step occurs first in transmission at a chemical synapse? Ostep 1 occurs first step 2 occurs first step 3 occurs first step 4 occurs first Ostep 5 occurs firstarrow_forwardWhat can occur to the neurotransmitter after being released from the synaptic vesicle? Give a real life example of this.arrow_forwardRlvastigmine is a cholinesterase inhibitor medication that alleviates symptoms in Alzheimer's and Parkinson's disease. Label the following diagram of a synapse during this process.arrow_forward
- If a synapse is said to be axodendritic, that means that the __________________ is the presynaptic compartment and the ____________________ is the postsynaptic compartment.arrow_forwardIdentify the following as properties of electrical synapses, chemical synapses, or botharrow_forwardCystic fibrosis is a degenerative disease that causes the progressive breakdown of the myelin sheaths around the axons of neurons. Which of the following best describes the likely effect of cystic fibrosis on neuronal function? A B C D an inhibition in the release of neurotransmitters at the synaptic terminal a decrease in the conduction speed of the action potential along neuronal axons an unstoppable generation of action potential in affected neurons an inhibition in the generation of action potentials at neuronal dendritesarrow_forward
- Which of the following statements concerning synapses is FALSE? O A) Modulation of synaptic strength can be presynaptic of postsynaptic B) High frequency stimulation in the presynaptic neuron often leads to DECREASED neurotransmitter release O C) Modulation of synaptic strength can either be short term, lasting seconds, or long term, lasting as long as a lifetime. D) Agonists are drugs that mimic neurotransmitters and antagonists are drugs that block the action of neurotransmitters O E) Certain drugs prevent the reuptake of neurotransmitter from the synapsearrow_forwardLet’s say the synapses of a neuron’s dendrites are filled with glutamate-gated channels which, when activated by glutamate, cause an excitatory postsynaptic potential (EPSP) in the neuron. In one instance, glutamate is released at all of the synapses simultaneously and this leads to an action potential in the neuron. A) What type of summation of PSPs is this? Why? B) List the sequence of steps that occur starting from binding of glutamate to the glutamate-gated channels at the synapses and ending with the membrane potential at the axon hillock returning to resting potential at the end of the action potential. (Include all the changes in voltage-gated channels underlying the action potential.)arrow_forwardWhat type of synaptic potential (if any; be sure to indicate if any modification is occurring as well) would occur if: a.) An MAO inhibitor type of antidepressant is functioning at an active dopaminergic synapse that increases the rate of sodium flowing into the cell. b.) Prozac is present at an active serotonin synapse where receptor activation increases the flow of potassium out of the cell.arrow_forward
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