Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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Chapter 11, Problem 5CCS
Nursing Student with Neuropathic Pain
Tamara Costa broke her right tibia and has undergone two separate surgeries to repair it. Although the bone has healed, she suffers increasing pain around the incision sites. The painful area covers the lateral surface of her right leg. She can't stand wearing anything over it or even having a sheet touch it. Her diagnosis is postsurgical neuropathic pain. Pain medication has not helped.
Tamara is a second-year nursing student and has done some reading to try to understand her problem and perhaps find a solution. She has found an article that says neuropathic pain may be caused by a decreased threshold for action potential generation in pain-detecting neurons. However, she has forgotten some of her physiology and needs some help in understanding what she is reading. She has logged into the “Ask a Nurse" chat line–and she got you!
5. You’ve found a copy of the same article, and see that it identifies other ways pain inhibition could decrease. Explain each of them:
a. A decrease in the number of receptors for the inhibitory neurotransmitter GABA.
b. A local decrease in the amount of Cl-outside the cell. (Hint: GABA opens Cl–channels, allowing Cl– influx into the postsynaptic cell.)
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Chapter 11 Solutions
Human Anatomy & Physiology (11th Edition)
Ch. 11 - Prob. 1RQCh. 11 - 2. Match the names of the supporting cells found...Ch. 11 - 4. Assume that an EPSP is being generated on the...Ch. 11 - 5. The velocity of nerve impulse conduction is...Ch. 11 - 6. Chemical synapses are characterized by all of...Ch. 11 - Prob. 5RQCh. 11 - Prob. 6RQCh. 11 - 9. Inhibition of acetylcholinesterase by poisoning...Ch. 11 - 8. The anatomical region of a multipolar neuron...Ch. 11 - 11. An IPSP is inhibitory because (a) it...
Ch. 11 - 12. Identify the neuronal circuits described by...Ch. 11 - 13. Explain both the anatomical and functional...Ch. 11 - 14. (a) Describe the composition and function of...Ch. 11 - 15. (a) What is myelin? (b) How does the...Ch. 11 - 16. (a) Contrast unipolar, bipolar, and multipolar...Ch. 11 - 17. What is the polarized membrane state? How is...Ch. 11 - 18. Describe the events that must occur to...Ch. 11 - 19. Since all APs generated by a given nerve fiber...Ch. 11 - 20. (a) Explain the difference between an EPSP and...Ch. 11 - 21. Since at any moment a neuron is likely to have...Ch. 11 - Prob. 22RQCh. 11 - Prob. 13RQCh. 11 - 25. Briefly describe the three stages of neuron...Ch. 11 - 2. Local anesthetics block voltage-gated Na+...Ch. 11 - 3. When admitted to the emergency room, Sean was...Ch. 11 - 4. Rochelle developed multiple sclerosis when she...Ch. 11 - 5. In the Netherlands a young man named Jan was...Ch. 11 - Nursing Student with Neuropathic Pain Tamara Costa...Ch. 11 - Nursing Student with Neuropathic Pain Tamara Costa...Ch. 11 - Nursing Student with Neuropathic Pain
Tamara...Ch. 11 - Nursing Student with Neuropathic Pain Tamara Costa...Ch. 11 - Nursing Student with Neuropathic Pain Tamara Costa...
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