Molecular Cell Biology
Molecular Cell Biology
8th Edition
ISBN: 9781464183393
Author: Harvey Lodish, Arnold Berk, Chris A. Kaiser, Monty Krieger, Anthony Bretscher, Hidde Ploegh, Angelika Amon, Kelsey C. Martin
Publisher: W. H. Freeman
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Chapter 11, Problem 10RTC
Summary Introduction

To analyze:

Which pump is inhibited by the drugs used to reduce the secretion of acid in the stomach and where is the pump located?

Introduction:

The hydrochloric acid is released by the parietal cells of the stomach, which reduces the pH of the stomach, however, the cytosolic pH of the cells is neutral due to the functioning of ion pumps. The hydrochloric acid kills the pathogens that enter the body along with food and reduces the pH for the digestive juices to function.

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