Essentials of Genetics (9th Edition) - Standalone book
9th Edition
ISBN: 9780134047799
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino
Publisher: PEARSON
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Chapter 1, Problem 15PDQ
If you knew that a devastating late-onset inherited disease runs in your family (in other words, a disease that does not appear until later in life) and you could be tested for it at the age of 20, would you want to know whether you are a carrier? Would your answer be likely to change when you reach age 40?
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4.
You find that all four flower color genes map to the second
chromosome, and perform complementation tests with deletions for each
gene. You obtain the following results:
(mutant a = blue, mutant b = white, mutant c = pink, mutant d = red)
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Results of Complementation tests
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Mutant a
b
с
Del (2.2 -2.6)
blue
white
pink
purple
Del (2.3-2.8)
blue
white
pink
red
Del (2.1 -2.5)
blue
purple
pink
purple
Del (2.4-2.7)
purple
white
pink
red
C
d
Indicate where each gene maps:
a
b
ori ai indW (anioq 2) .8
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1. Below is a pedigree of a rare trait that is associated with a variable number
repeat. PCR was performed on individuals using primers flanking the VNR,
and results are shown on the agarose gel below the pedigree.
I.1 1.2 II.1 II.2 II.3 II.4 II.5 II.6 11.7 III.1 III.2 III.3 III.4etum
A. (5 points) What is the mode of inheritance?
B. (10 points) Fill in the expected gel lanes for II.1, II.5, III.2, III.3 and III.4
C. (5 points) How might you explain the gel results for II.4?
To study genes that create the purple flower color in peas, you isolate 4 amorphic mutations. Each results in a flower with a different color, described
mutant a = blue
mutant c = pink
mutant b = white
mutant d = red
A. In tests of double mutants, you observe the following phenotypes:
mutants a and b = blue
mutants b and c = white
mutants c and d = pink
Assuming you are looking at a biosynthetic pathway, draw the pathway indicating which step is affected by each mutant.
B. What is the expected flower color of a double mutant of a and c?
Chapter 1 Solutions
Essentials of Genetics (9th Edition) - Standalone book
Ch. 1 -
1. Describe Mendel’s conclusions about how...Ch. 1 -
2. Review the Chapter Concepts list on p. 1....Ch. 1 - What is the chromosome theory of inheritance, and...Ch. 1 - Prob. 4PDQCh. 1 -
5. Given the state of knowledge at the time of...Ch. 1 - Contrast chromosomes and genes.Ch. 1 - How is genetic information encoded in a DNA...Ch. 1 - Describe the central dogma of molecular genetics...Ch. 1 - How many different proteins, each with a unique...Ch. 1 - Outline the roles played by restriction enzymes...
Ch. 1 - What are some of the impacts of biotechnology on...Ch. 1 - Prob. 12PDQCh. 1 - We all carry about 20,000 genes in our genome. So...Ch. 1 - How has the use of model organisms advanced our...Ch. 1 - If you knew that a devastating late-onset...Ch. 1 -
16. Why do you think discoveries in genetics...
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