Human Biology: Concepts and Current Issues Plus Mastering Biology with Pearson eText -- Access Card Package (8th Edition)
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Chapter 1, Problem 12TY
Summary Introduction

Introduction:

Predictions and hypotheses are often tested using carefully designed experiments. These experiments need to be controlled experiments. This essentially means that no other variable, apart from the one being tested for, must affect the outcome. The variables involved can be independent variables or dependent variables. Independent variables are those which stand alone and are not changed by the variable we wish to measure. These include time, age, distance, drug treatment, and no drug treatment. Dependent variables are those which are dependent on an independent variable. Examples are growth or blood pressure. Experiments are designed in a way so that only one independent variable is manipulated or controlled.

An experiment designed to test the effectiveness of a drug would start with picking a large number of suitable subjects for that experiment. These are then randomly divided among experimental and control groups. Everything else for both the groups is kept exactly the same apart from the controlled variable, which is the administration of the drug. Experimental group would get the drug and control group would receive an identical pill but with no drug which is the placebo. The results of the two groups are then compared to see the effect of the drug.

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Which of the following statements is not true?   a. Some RCTs may involve "cross-over" as part of their design   b. Community trials may or may not involve randomization   c. The participants for a randomized controlled trial must be randomly selected from the target population   d. All RCT participants randomized into the treatment group and the control group must be included in data analysis, even if some of them  did not complete the study
What is the purpose of randomization in a randomized controlled trial?    a. To ensure that there are fewer adverse effects   b. To ensure that participants are unaware as to whether they are receiving the medicine or the placebo   c. To ensure that participants in the treatment group and those in the pacebo (or control) group are as similar as possible when the study begins   d. To ensure that participants in the trial are representative of the target population
Which of the following statements are true about the Hatch-Waxman Act? Select one or more: a. The Act benefits the manufacturer of reference drugs by extending the patent. O b. The Act benefits the manufacturer of reference drugs by eliminating reporting requirements for changes in the manufacturing process. O c. The Act benefits the manufacturer of generics drugs by eliminating reporting requirements for changes in the manufacturing process. O d. The Act benefits the manufacturer of generics drugs by eliminating the need for clinical trials.

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Human Biology: Concepts and Current Issues Plus Mastering Biology with Pearson eText -- Access Card Package (8th Edition)

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