Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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You are teaching a class on the regulation of eukaryotic gene expression. In order to demonstrate this complex process, you decide to draw for the class a typical eukaryotic gene/transcription unit with its major regions, such as the promoter regions, where the RNA polymerase II and transcription factors would bind
From the list given - choose all components that you think are part of a typical eukaryotic gene
From the list given - choose all the regulatory sequences that you think would control the expression of this eukaryotic gene
From the list given - choose all of the regulatory proteins that would bind the eukaryotic gene to control its expression
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- a) Define the term gene expression b) State 4 difference between prokaryotes and eukaryotes gene expression c) state the importance of regulating gene expressionarrow_forwardChoose ONE example of control of gene expression in eukaryotes and describe it in detail. Identify which of the five levels of regulation of gene expression your example represents and explain how your example benefits the cell in which it takes place.arrow_forwardLet's say there is an eukaryotic gene that has five exons and 4 introns. If the GU sequence at the 5' splice site of the third intron is deleted, describe how this is going to affect the expression of this gene. draw the mature mRNA too.arrow_forward
- General transcription factors Select an answer and submit. For keyboard navigation, use the up/down arrow keys to select an answer. a a) act at every gene for a given RNA pol b b) act only at specific genes for under specific conditions c) must be very close to the promoter C d) none of the abovearrow_forwardConsider gene expression in a prokaryotic or bacterial cell. Which of the following is true for transcription in this cell? Select all that apply. During Transcription, the enzyme topoisomerase relaxes negative supercoiling in the DNA strands MRNA can be synthesized by Transcription and at the same time this mRNA can be used for protein synthesis or Translation MRNA has to be processed before leaving the nucleus RNA polymerase requires sigma factor for efficient transcription initiationarrow_forwardIf the operator gene is a non-transcribable region of DNA, and the promoter is upstream of the operator, what does this mean for the operator gene during transcription? Does it get removed before? Or is it always an intron that gets spliced out?arrow_forward
- A bacterial species has a hypothetical sigma promoter that has the following sequence: TTGGCA - 18 bases - TATAAT What change in the level of transcription would there be if the sequence was mutated to: TTCGCA -18 bases -TATAAT O The mutation would bind the promoter to the consensus and produce normal levels of transcription O The mutation would inhibit the promoter thereby inhibiting transcription The mutation would move the promoter away from consensus and reduce the level of transcription O No change the consensus TATAAT sequence in the same. D00 F3 F4 F5 F6 F7 F8 F9 % & 5 6 7 8 9 %24arrow_forwardAfter further investigation, you discovered that HHT1 and HHT2 are produced via alternative splicing. HHT1 is expressed in the liver, and HHT2 is expressed in the pancreas. Regarding the regulation of their expression, you conclude: all answers are possible the regulation occurs at the epigenetic level the regulation occurs at the transcriptional level the regulation occurs at the level of splicingarrow_forwardGene X codes for a protein in eukaryotes. A mutated eukaryotic cell contains an altered base-pair in an intron of gene X. Which would be the most likely effect of this mutation on the biomolecules in the cell? The amount of pre-mRNA transcribed from gene X would be less than normal. The amount of functional protein corresponding to gene X would be less than normal. The ability of snRNAs to form a spliceosome would be diminished. The breakdown of mature mRNA corresponding to gene X would be fasterarrow_forward
- Describe four differences between prokaryotic and eukaryotic gene expression.arrow_forwardLack of phosporylation of the C-terminal domian of Pol Il will result in which of the following? O Assembly of the full set of general transcription factors plus Pol II at the promoter, but unphosphorylated Pol II cannot leave the promoter region No assembly of the general transcription factors at a promoter No binding of Pol II at a promoter The unphosphorylated Pol II can initiate and elongate but cannot terminatearrow_forwardWhich of the following statements is false? a mutation in a 5' or 3' splice site must alter the sequence of the protein encoded by a gene a missense mutations replaces one amino acid with a different amino acid a mutation in a promoter is unlikely to alter the sequence of the polypeptide encoded by a gene a mutation in a transcriptional terminator is unlikely to alter the sequence of a protein encoded by a gene. a frameshift mutation changes the sequence of a protein 0000arrow_forward
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