Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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You are teaching a class on the regulation of eukaryotic gene expression. In order to demonstrate this complex process, you decide to draw for the class a typical eukaryotic gene/transcription unit with its major regions, such as the promoter regions, where the RNA polymerase II and transcription factors would bind
From the list given - choose all components that you think are part of a typical eukaryotic gene
From the list given - choose all the regulatory sequences that you think would control the expression of this eukaryotic gene
From the list given - choose all of the regulatory proteins that would bind the eukaryotic gene to control its expression
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- Choose ONE example of control of gene expression in eukaryotes and describe it in detail. Identify which of the five levels of regulation of gene expression your example represents and explain how your example benefits the cell in which it takes place.arrow_forwardLet's say there is an eukaryotic gene that has five exons and 4 introns. If the GU sequence at the 5' splice site of the third intron is deleted, describe how this is going to affect the expression of this gene. draw the mature mRNA too.arrow_forwardGeneral transcription factors Select an answer and submit. For keyboard navigation, use the up/down arrow keys to select an answer. a a) act at every gene for a given RNA pol b b) act only at specific genes for under specific conditions c) must be very close to the promoter C d) none of the abovearrow_forward
- If the operator gene is a non-transcribable region of DNA, and the promoter is upstream of the operator, what does this mean for the operator gene during transcription? Does it get removed before? Or is it always an intron that gets spliced out?arrow_forwardA bacterial species has a hypothetical sigma promoter that has the following sequence: TTGGCA - 18 bases - TATAAT What change in the level of transcription would there be if the sequence was mutated to: TTCGCA -18 bases -TATAAT O The mutation would bind the promoter to the consensus and produce normal levels of transcription O The mutation would inhibit the promoter thereby inhibiting transcription The mutation would move the promoter away from consensus and reduce the level of transcription O No change the consensus TATAAT sequence in the same. D00 F3 F4 F5 F6 F7 F8 F9 % & 5 6 7 8 9 %24arrow_forwardAfter further investigation, you discovered that HHT1 and HHT2 are produced via alternative splicing. HHT1 is expressed in the liver, and HHT2 is expressed in the pancreas. Regarding the regulation of their expression, you conclude: all answers are possible the regulation occurs at the epigenetic level the regulation occurs at the transcriptional level the regulation occurs at the level of splicingarrow_forward
- Which of the following statements is false? a mutation in a 5' or 3' splice site must alter the sequence of the protein encoded by a gene a missense mutations replaces one amino acid with a different amino acid a mutation in a promoter is unlikely to alter the sequence of the polypeptide encoded by a gene a mutation in a transcriptional terminator is unlikely to alter the sequence of a protein encoded by a gene. a frameshift mutation changes the sequence of a protein 0000arrow_forwardWhat role does an operator sequence serve in bacterial gene expression regulation? Describe one change in bacterial cells that can cause a repressor protein to go from inactive to active or from active to inactive.arrow_forwardSuppose you had isolated a new transcription factor and wanted to know which genes this protein might regulate. Is there any way that you could use a cDNA microarray of the type shown in the picture to approach this question?arrow_forward
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