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Answer the following questions from 1-5

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What is the most likely mode of inheritance for the disease depicted in the following pedigree? I II III 1 1 2 1 2 autosomal recessive autosomal dominant 3 3 2 4 4 5 5 6

I Review Lesch-Nyhan syndrome (OMIM 300322) is a rare X-linked recessive disorder that produces severe mental retardation, spastic cerebral palsy, and self- mutilation. Part A What is the probability that the first son of a woman whose brother has Lesch-Nyhan syndrome will be affected? Express your answer as a fraction (example 1/16). Submit Request Answer Part B If the first son of the woman described in (a) is affected, what is the probability that her second son is affected? Express your answer as a fraction (example 1/16). Submit Request Answer

both parents are recessive short, name the 4 possible offspring.

In fruit flies, the color of the eyes is sex linked (on the X chromosome). Complete the cross of the flies in the image to determine the possible offspring produced. Red eyes are dominant (R), White eyes are recessive (r). What percentage of the male offspring are expected to have red eyes? XR Y O a 100% O b 75% 50% Od 25% e 0% Saved at 11:42 am Review Answers JP

Finally, draw out a Punnett square to help you consider the cross between these possible gametes. Sex-Linked1 := Homework • Unanswered What are the possible genotypes of the offspring shown in your Punnett square? Select an answer and submit. For keyboard navigation, use the up/down arrow keys to select an answer. XBxb and xbY a b XBXB and xbY Neither of these answers is correct Unanswered • 1 attempt left Submit Sex-Linked2 Homework • Unanswered What are the possible phenotypes of the offspring? Select an answer and submit. For keyboard navigation, use the up/down arrow keys to select an answer. a Females with normal color vision and males who are colorblind Females who are colorblind and males who have normal color vision

Explain the following diagram. It refers to a pedigree on the disease called phenylketonuria. Briefly explain about the disease; specifically biochemical and genetic aspects. Then I interpret the pedigree. Say what type of inheritance the condition exhibits

C B 2089202222 a b d B А. a e The figure above shows images of five different cells. Each box contains an image that represents a cell of an AaBb dihybrid that is in some stage of meiosis or mitosis. The lines represent chromatids. The letters on the lines represent alleles. The shaded region shows the shape of the cell. Refer to this figure as you consider the questions below. Each box contains an image that represents a cell of an AaBb dihybrid that is in some stage of meiosis or mitosis. The lines represent chromatids. The letters on the lines represent alleles. The shaded region shows the shape of the cell. Refer to this figure as you consider the questions below. Each box represents a cell in meiosis or mitosis. The lines represent chromatids. The letters next to the lines represent alleles. The shaded region shows the shape of the cell. The A gene controls an X-linked trait. The B gene controls an autosomal trait. Refer to this figure as you consider questions X-Y below + 8)…