Chemistry
Chemistry
10th Edition
ISBN: 9781305957404
Author: Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher: Cengage Learning
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Write the mechanisms for all of the following reactions. Show curved arrows and an appropriate number
of elementary steps. If a mechanism provides stereoisomers, state the end result (e.g. racemic mixture,
mixture of diastereomers, etc.) As with all reactions, be careful with your charges.
A.
NBS
B.
C.
D.
OMe
Br
H-Br
dark
1) Br-Br
H₂O
2) LDA
NaOme
Et MeOH, heat
1) 2 equiv. LDA
2) Me-1 (1 equiv)
3) H₂O heat
Give mechanism through
step 2 and final product of
step 3
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Transcribed Image Text:Write the mechanisms for all of the following reactions. Show curved arrows and an appropriate number of elementary steps. If a mechanism provides stereoisomers, state the end result (e.g. racemic mixture, mixture of diastereomers, etc.) As with all reactions, be careful with your charges. A. NBS B. C. D. OMe Br H-Br dark 1) Br-Br H₂O 2) LDA NaOme Et MeOH, heat 1) 2 equiv. LDA 2) Me-1 (1 equiv) 3) H₂O heat Give mechanism through step 2 and final product of step 3
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