Wild type genomic sequence of a portion of a gene and the wild type sequence of portion of the protein gene product. The protein sequence only matches partially. TAT AAA GGG CGA CCA CCT GGT AAT GGG ACT TTG AGG Tyr Lys Gly Arg Pro Pro Ala Pro Arg Gln Tyr Trp Note: The five amino acids at the amino end of the WT protein match the coding sequence perfectly, but not the six at the carboxyl end. This is for an obvious reason that you should figure out before starting the problem. One of the difficulties with this problem is that you do not have the DNA sequence for the carboxyl end of the protein, but that should not be a problem! And, so far, there are no mutations; nothing unusual, it is just a normal eukaryotic gene!! A mutant is found that has the following protein sequence in that part of the protein: Tyr Lys Gly Arg Thr Cys Ser Premature Stop. What is the likely mutation? between A12 and C13 insert T. between C13 and C14 insert T. A15 -> del. C13 and C14 -> del. G8 -> T. G20 -> A. T21 -> del.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
icon
Related questions
Topic Video
Question
Wild type genomic sequence of a portion of a gene and the wild type sequence of portion of the protein gene
product. The protein sequence only matches partially.
ТАT AAA GGG СGA ССА ССТ GсT AАT GGG АСт тTG AGG
Tyr Lys Gly Arg Pro Pro Ala Pro Arg Gln Tyr Trp
Note: The five amino acids at the amino end of the WT protein match the coding sequence perfectly, but not
the six at the carboxyl end. This is for an obvious reason that you should figure out before starting the
problem. One of the difficulties with this problem is that you do not have the DNA sequence for the carboxyl
end of the protein, but that should not be a problem! And, so far, there are no mutations; nothing unusual, it is
just a normal eukaryotic gene!!
A mutant is found that has the following protein sequence in that part of the protein:
Tyr Lys Gly Arg Thr Cys Ser Premature Stop. What is the likely mutation?
between A12 and C13 insert T.
between C13 and C14 insert T.
A15 -> del.
C13 and C14 -> del.
G8 -> T.
G20 -> A.
T21 -> del.
Transcribed Image Text:Wild type genomic sequence of a portion of a gene and the wild type sequence of portion of the protein gene product. The protein sequence only matches partially. ТАT AAA GGG СGA ССА ССТ GсT AАT GGG АСт тTG AGG Tyr Lys Gly Arg Pro Pro Ala Pro Arg Gln Tyr Trp Note: The five amino acids at the amino end of the WT protein match the coding sequence perfectly, but not the six at the carboxyl end. This is for an obvious reason that you should figure out before starting the problem. One of the difficulties with this problem is that you do not have the DNA sequence for the carboxyl end of the protein, but that should not be a problem! And, so far, there are no mutations; nothing unusual, it is just a normal eukaryotic gene!! A mutant is found that has the following protein sequence in that part of the protein: Tyr Lys Gly Arg Thr Cys Ser Premature Stop. What is the likely mutation? between A12 and C13 insert T. between C13 and C14 insert T. A15 -> del. C13 and C14 -> del. G8 -> T. G20 -> A. T21 -> del.
Expert Solution
trending now

Trending now

This is a popular solution!

steps

Step by step

Solved in 2 steps

Blurred answer
Knowledge Booster
Mitochondrial mutations
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:
9780134580999
Author:
Elaine N. Marieb, Katja N. Hoehn
Publisher:
PEARSON
Biology 2e
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax
Anatomy & Physiology
Anatomy & Physiology
Biology
ISBN:
9781259398629
Author:
McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:
Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:
9780815344322
Author:
Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:
W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:
9781260159363
Author:
Martin, Terry R., Prentice-craver, Cynthia
Publisher:
McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Inquiry Into Life (16th Edition)
Biology
ISBN:
9781260231700
Author:
Sylvia S. Mader, Michael Windelspecht
Publisher:
McGraw Hill Education