Why is triose phosphate isomerase considered to be catalytically perfect?

Q: How does chorismate mutase destabilize the ground state of its substrate?

A: Chorismate mutase It is an enzyme involved in shikimate pathway for the formation of phenylalanine…

Q: What is the metabolic role of aspartate transcarbamoylase?

A: Aspartate transcarbamoylase catalyzes the first biochemical reaction in pyrimidine biosynthesis. It…

Q: what is the key enzyme of the pentose phosphate pathway also serving as the dirst enzyme of the…

A: The initial metabolite of the pentose phosphate pathway is glucose-6-phosphate, 2 NADP+, and H2O.…

Q: What is alpha keto glutarate dehydrogenase complex?. explain very briefly.

A: Tri carboxylic acid (TCA) cycle is an amphibolic pathway that means it involves both catabolic and…

Q: What are some types of enzyme-catalyzed reactions that require pyridoxal phosphate as a coenzyme?

A: Pyridoxal phosphate serves as a coenzyme for several enzyme-catalyzed reactions. It is an active…

Q: If you were to determine the P/O ratio for oxidation of a-ketoglutarate, you would probably include…

A: The P/O ratio or Phosphate/Oxygen ratio refers to the amount of ATP produced from the movement of…

Q: What is the biochemical relevance of cori cycle

A: Introduction: The chemical reactions that occur within the living body for the production of energy…

Q: What kind of inhibitor is threo-sphingosine? Explain this type of inhibition.

A: Introduction:  Enzymes are the catalyst of life. Enzyme inhibitor is defined as a substance which…

Q: Chymotrypsin is a digestive enzyme with a catalytic optimum between pH 7.8 and 8.0. However, due to…

A: Proteases are enzymes that cleave peptide bonds that link two amino acid residues together.…

Q: What is formed when serine 195 acts as a nucleophile on the carbonyl carbon of the peptide bond?…

A: A catalyst is a molecule that can increase the rate of a chemical reaction. The amount of catalysts…

Q: How is synthesis and degradation of fructose-2,6-bisphosphate achieved?

A: Fru-2,6-P2, or fructose 2,6-bisphosphate, is a metabolite that regulates glycolysis and…

Q: In what condition and why is pyruvate converted to lactate?

A: Pyruvic acid is produced as a product of glycolysis, which is the anaerobic metabolism of glucose.…

Q: Seduheptulose is an intermediate in respiratory and photosynthetic pathways and plays a vital role…

A: a. The stable form of sugars like pentose and hexose sugars are five or six-atom rings and these…

Q: What are the nonoxidative reactions of the pentose phosphate pathway, and why are they important?

A: Pentose phosphate pathway is an alternative to glycolyis and TCA cycle for oxidation of glucose.…

Q: With respect to stereochemistry, what is unique about the reaction catalyzed by aconitase?

A: Aconitase is an enzyme that catalyzes stereo-specific isomerization which was an essential enzyme in…

Q: Mercuric ion and methanol are inhibitors of alcohol dehydrogenase. Explain.

A: Alcohol (ADH) dehydrogenase is an enzyme that helps in the interconversion of alcohol into ketones…

Q: An inhibitor that specifically labels chymotrypsin at histidine 57 is N-tosylamido-l-phenylethyl…

A: Trypsin is an enzyme that helps to digest protein. It breaks down the process of digestion that…

Q: [methyl-14C]Pyruvate was administered to isolated liver cells in the presence of sufficient malonate…

A: Succinate dehydrogenase or respiratory complex II is an enzyme complex, found in many bacterial…

Q: What is the enzyme classification of the catalyst used in the conversion of dihydroxyacetone…

A: Triose-phosphate isomerase Enzyme that catalyzes the reversible interconversion dihydroxyacetone…

Q: Peroxisomes have an alternative pathway for oxidizing polyunsaturated fatty acids. They contain a…

A: Consider linoleate, a C18 polyunsaturated fatty acid with cis-∆9 and cis-∆12 double bonds. When…

Q: Phosphopentose isomerase interconverts the aldose ribose 5-phosphate and the ketose ribulose…

A: the reaction is the part of the oxidative phase of the pentose phosphate pathway this is the last…

Q: 10.32 Give an explanation for the Lineweaver-Burk plot for a certain enzyme-catalyzed reaction shown…

A: Michaelis Menten equation describes the mathematical relationship between initial rate of reaction…

Q: How can we test the validity of the mechanism proposed for the catalytic triad?

A: A set of the 3 coordinated amino acids that can be present on the active site of some of the enzymes…

Q: Why is oxaloacetate an intermediate in gluconeogenesis?

A: Glucose is the primary source of energy in the body. Glucose is broken down into pyruvate by…

Q: What is the mechanism of an enzyme reaction involving a coenzyme for Redox Rxns?

A: Enzymes are a class of proteins that performs various activities in the living body. They are also…

Q: Why does it make metabolic sense for UTP to inhibit carbamoyl phosphate synthetase II, whereas ATP…

A: Feedback inhibition is a cellular control mechanism in which the activity of the enzyme is inhibited…

Q: What product will accumulate if the there is a degradation defect involving the given amino acids?…

A: As you have posted multiple questions, I am only answering the first question as we are authorized…

Q: What acyl group does transketolase transfer to ribose-5-P?

A: Introduction: The end products of pentose phosphate pathway are pentoses and NADPH.

Q: What is the catalytic triad on chymotrypsin? Detail its importance.

A: Proteases are hydrolytic enzymes that cleave peptide bonds that link two amino acid residues…

Q: Why is the TCA cycle is important for both anabolic and catabolic reactions?

A: After each turn of the TCA cycle, oxaloacetate is regenerated and can combine with another…

Q: 5. Describe the role of His in the catalytic mechanism shown.

A: Enzymes are highly specialized proteins that have extraordinary catalytic power, greater than that…

Q: The isoelectric point (pI) of 6-phosphogluconate dehydrogenase is 6.0.  Explain why the buffer used…

A: Enzymes are a class of proteins except for ribozymes (class of RNA) that elevates the pace of the…

Q: Why is gluconeogenesis labeled as enzymatic by-pass reactions?

A: Glucose is a central carbohydrate in body. It is the instant energy generating molecule. Whenever…

Q: What are cofactors and coenzymes in an enzymatic reaction? Is tetrahydro- folate considered a…

A: Enzymes require cofactor and coenzyme for their activity.

Q: The allosteric properties of aspartate transcarbamoylase have been discussed in detail in this…

A: Aspartate Transcarbamoylase (ATCase) is a regulatory enzyme that has different catalytic and…

Q: What is the enzyme classification of the catalyst used in the conversion of oxalosuccinate to…

A: The catalyst (enzyme) involved in the conversion of oxalosuccinate to alpha-ketoglutarate is…

Functional Diversity