Why is proline frequently encountered at the places in the myoglobin and hemoglobin molecules where the polypeptide chain turns a corner?

Q: A peptide with the sequence isoleucine1-aspartate2-valine3-lysine4-proline5-glutamate6 is located at…

A: Amino acids combine to form proteins by the formation of peptide bond. Amino acids have a one amino…

Q: Many of the loops on proteins are composed of hydrophilic amino acids. Why might this be the case?

A: Protein is one of the important biomolecules. This protein is made up of sequence amino acids which…

Q: amino acid in the form of a "phenylthiohydantoin" (PTH-amino acid), are shown below. What is the…

A: Phenyl isothiocynate is the Edman reagent. It reacts with N-terminal amino acid to give phenyl…

Q: How is the peptide shown named (give each 3-letter name for the amino acids present)? Whichamino…

A: The peptide is made up of amino acid. The sequence of amino acid in this peptide is N - Val-Phe-Trp-…

Q: Arginine has three ionizable groups. The pK of α-COOH is 2.18; α-NH 3 + , 9.09; and the R-group,…

A: Isoelectric point (pI) is the pH at which the net electric charge of the amino acid is zero. When,…

Q: What would the tertiary structure of the dipeptide Asp-Ser be if it was made into a polypeptide…

A: Since you have posted a question with multiple sub-parts, we will solve first three sub-parts for…

Q: So which form of the arginine side chain is the ionized form? And when the side chain is ionized the…

A: Arginine is an amino acid with a side chain that contains a guanidine group. In its conjugate acid…

Q: Would the side chains in the Leu-Thr-Met-Val-Trp-Gly-Pro of a polypeptide be located on the interior…

A: 1.Amino acids that are hydrophobic (water-fearing) in nature are mostly found interior of the…

Q: What does the high-energy molecules adenosine triphosphate fforms and reduced forms of nicotinamide…

A: A high-energy molecule is adenosine triphosphate (ATP). It is created by cells and used as a source…

Q: Remembering that the amino acid side chains projecting from each polypeptide backbone in a β sheet…

A: Amongst secondary structures of polypeptide chains made of amino acids, β-sheets are a more spacious…

Q: what is the N and C terminal AA residue?

A: DNA sequencing is a biochemical method for determining the order of the nucleotide bases, adenine,…

Q: A protein contains three 60-kD polypeptides and six 20-kD polypeptides. Each 60-kD chain is…

A: Electrophoresis means migration of charged particles under the influence of an electric…

Q: The endorphins are a group of naturally occurring neurotransmitters that act in a manner like…

A:

Q: An a-Helix (or helices) is often found at anion binding sites of different proteins. Explain this…

A: Helices are spring like structure which forms through the hydrogen bonding between C=O of the ith…

Q: Some bacteria produce poly-γ-glutamic acid, a polymer in which the amino group of each glutamate…

A: Poly-γ-glutamic acid (γ-PGA) is a highly promising polymer that is non-toxic, non-immunogenic and…

Q: A) describe in molecular detail how protonation of the histidine side-chain results in hemoglobin's…

A: Hemoglobin is the primary protein responsible for the transport of oxygen from lungs to different…

Q: With the aid of a simple generic diagram: i) IDENTIFY and EXPLAIN how the type(s) of chemical…

A: The downloaded image of the 3GRS structure from PDB is as shown. This is the structure of Glutathion…

Q: Which amino acid pair constitutes the hydrophobic patch on sickle cell hemoglobin that results in…

A: Sickle cell disease is caused due to inversion of one base pair (A -> T). Due to which, the sixth…

Q: Consider the following pKa values: terminal amino group: 9.5; C = 8.2; Y = 10.1; K= 10.5; terminal…

A: Isoelectronic point is defined as the pH at which the amino acid does not move in an electric field.…

Q: Nucleotides containing ribose, thymine, and phosphate are not found in ribonucleic acids. Explain…

A: RNA consists of ribonucleic acid, which exhibit ribose, and nitrogenous bases.

Q: (a) A decapeptide has the following amino acid composition: Alaz, Arg, Cys, Glu, Gly, Leu, Lys, Phe,…

A: Since you have asked multiple questions, we will solve the first question for you. If you want any…

Q: 1. The graph given represents a size-exclusion chromatogram after the refolding of the hemoglobin…

A: Chromatography is a technique of protein purification in which protein can be separated based on its…

Q: What is the second major form of arginine at pH 8.0? What fraction is in this form?

A: Arginine is one of the twenty standard amino acids which take part in the synthesis of proteins…

Q: Using the letter “R" to indicate amino acid side chain, draw the following: A. The backbone atoms…

A: Beta-sheets come in the category of secondary structure of proteins. In parallel beta-sheets, two…

Q: Assume that the 3 polypeptide strands shown below form a parallel B-sheet. Select amino acids AA1,…

A: Beta sheet is one of type of secondary structure in which inter strand hydrogen bonds is formed…

Q: Sickle cell anemia is a horrific molecular disease that causes a multitude of issues within the…

A: Mutations are notorious to cause many horrifying diseases in humans . They can decrease the quality…

Q: What does this statement mean: "Upon folding of a protein many main chain amides replace their…

A: Polypeptide chains are composed of amino acids bonded to each other via peptide bonds. Peptide bonds…

Q: 1. The shape of hemoglobin binding curves is: hyperbolic or sigmoidal 2. a) Based on the binding…

A: Note: As per the guidelines, i could solve only the first three subparts of the question. Please re…

Q: What are relatively small proteins with a preponderance of the basic, positively charged amino acids…

A: Amino acid such as lysine, arginine, and histidine has basic positively charged groups in their side…

Q: Consider the following two peptides: I. Ile-Trp-Ala-Met and II. Glu-His-Cys-Thr Which peptide would…

A: Peptides are short chains of amino acids that are linked together by peptide bonds. Amino acids are…

Metabolic pathways

Metabolism is defined as the group of life-supporting, enzyme-mediated chemical reactions in organisms. A metabolic pathway is a set of these chemical reactions that involve anabolism (synthesis of complex biomolecules) and catabolism (breakdown of biomolecules into small molecules) that occur inside a cell. Metabolites are the reacting substances, products, and intermediate substances of an enzymatic process that are altered by a series of chemical events catalyzed by enzymes.