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- What are the uses of cardiac troponins?1) If a heart lacked gap junctions, an organ-level contraction would occur.True/False 2) We care about mean arterial pressure specifically because we care about having an appropriate rate of blood flow through capillaries. True/False 3) A person's L-type channels are mutated so that they do not inactivate. How would this affect the time duration of a cardiac action potential? Group of answer choices a)Increase b)No change c)Decrease 4) A person's L-type channels are mutated so that they do not inactivate. How would this affect the time duration of a cardiac muscle cell contraction? Group of answer choices a)Increase b)No change c)DecreaseWhat is the importance and the physiology of the cardiac conduction system?
- What are the difference between contractile cells of the heart and electrical cells responsible for generation and conduction of impulses. Why is the cardiac action potential propagated more slowly in an AV node cell than in an atrial or ventricular myocyte? How are the channels and ions that are responsible for depolarization and repolarization work? How can be AV conduction affected by hypokalemia?Figure shows the conduction system of the heart that transmit the electrical impulses for the coordination of cardiac cycle. a) Referring to the Figure , which part of the heart's electrical conduction is known as the “pacemaker” of the heart? b)Explain how D controls atria and ventricles which causes ventricular systole.a) A consequence of the Frank-Starling law of the heart is that the outputs of the right and left ventricles match. Explain why this is important and how this match is made.b) The excitation-contraction matching mechanism within the heart muscle is different from that of the skeletal muscle. How might these differences be related to the difference between action potentials in cardiac muscle and skeletal muscle?
- What are the three populations of cells in the heart that can act as pacemakers? How do they differ?1)An increase in total peripheral resistance, all else remaining the same, will cause an increase in mean arterial pressure.True/False 2) We care about mean arterial pressure specifically because we care about having an appropriate rate of blood flow through capillaries. True/False 3) A person's L-type channels are mutated so that they do not inactivate. How would this affect the time duration of a cardiac action potential? Group of answer choices a)Increase b)No change c)Decrease 4) A person' L-type channels are mutated so that they do not inactivate. How would this affect the time duration of a cardiac muscle cell contraction? Group of answer choices a)Increase b)No change c)DecreaseDescribe the action potential of an autorhythmic cell in the heart.a) Indicate how the opening and closing of each ion channel affects the membrane potential of the cell.b) Provide one similarity between the action potential of an autorhythmic cell and the action potential of a neuron.c) Provide one difference between the action potential of an autorhythmic cell and the action potential of a neuron.
- Diagram electrical conduction of the heart and discuss each component (SA node, AV node, etc). How does this dictate the fluidity of heart contraction? Why does the SA always start the conduction? What is the inherent rate of depolarization of the SA node (this means that if the nervous system was shut off what would resting bpm be)? If it is damaged what happens to the electrical conduction system?Pressure changes that occur during the cardiac cycle are responsible for what two physiologic processes within the heart?If all plasma membrane Ca21 channels in contractile cardiac muscle cells were blocked with a drug, what would happen to the muscle’s action potentials and contraction?