Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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Why is it important for a transcription factor/activator to have a high affinity for a specific DNA sequence?
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- What is the function of the repressor CI? What is its importance in protein biology?arrow_forwardThe Iron Response Factor (IRF) protein regulates production of both the iron transport protein transferrin, which imports iron into a cell, and the iron storage protein ferritin, which stores iron when the cell has more iron than in needs. IRF is an RNA binding protein, which binds to a specific RNA sequence, the Iron Response Element (IRE). When the IRF protein binds to the IRE sequence in the mRNA that codes for transferrin, what effect does this have on the expression of transferrin? Briefly explain why this effect is observed.arrow_forwardQuestion 6 VCJD is caused by which pathogen? O A bacterial species. O A Prion. O A virus. O A protozoan. Question 7 Which virus listed below.can.causearrow_forward
- Determine whether the following will increase or decrease gene expression: mRNA degradation mRNA capping Binding of a transcriptional activator Ubiquitination of a protein and targeting to the proteasomearrow_forwardHeritable effects of gene expression that are not caused by a change in DNA sequence are called epigenic changes. What causes these changes?arrow_forwardProvide the major molecules and organelles involved in transcription.arrow_forward
- What does it mean to study the subcellular localization of a protein? What are two techniques that could be used to study the subcellular localization of a protein? Then specify how each of these techniques could be used to study a transcription factor in liver cellsarrow_forwardBecause DNA is found in the nucleus, transcription is a nuclear-localized process. Ribosomes responsible for protein synthesis are found in the cytoplasm. Why is hnRNP trafficking to the cytoplasm restricted to the nuclear pore complexes?arrow_forward
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