Which statement is true for the heme group present myoglobin:     a. Oxygen binding to heme group is influenced by serine residues within proteins’ sequences.     b. Oxygen binding to heme can become irreversible as a result of interaction with certain protein residues.     c. Oxygen reversibly binds to the heme prostetic group and this binding is influenced by histidine residues within the myoglobin sequence.     d. The heme group dissociates from Mb after oxygen is released.

One of the following is NOT correct regards haptoglobin  A. is a strong acute-phase protein, increases 1000-folds shortly after inflammation B. is α2-glycoprotein C. Prevents iron loss through the kidneys D. is decreased in liver disease and haemolytic anemia E. None of the above

Suppose a hypothetical "molecule X" binds to hemoglobin (at a different site than the O2 binding site) and stabilizes the T state. How would you identify this effector? a. Positive homotropic effector b. Negative homotropic effector c. Positive heterotropic effector d. Negative heterotropic effector

Why is the decreased affinity of fetal hemoglobin for BPG advantageous? With fewer BPG molecules bound to heme, there are more heme residues available for O2 binding. O A. B. Decreased BPG binding biases the fetal hemoglobin toward the R state. C. More free BPG is available to bind to adult hemoglobin, resulting in a shift to the R state. BPG is more available to bind to fetal myoglobin. helping to release O2 in fetal muscle tissue. D. 47

If one were to infuse lactate into the blood stream during exercise via an I.V. catheter, which of the following physiological events would be observed?    a. A significant increase in the burning sensation experienced in the lungs during rigorous exercise   b. A decrease in exercise time to exhaustion (fatigue faster)   c. An increase in liver gluconeogenic activity    d. All of the above    e. Only A and B are correct

O2 bound to hemoglobin:   a. acts the same as physically dissolved oxygen   b. Comes off the hemoglobin (dissociates) more easily as you increase the oxygen partial pressure   c. exerts a partial pressure    d. Comes off the hemoglobin (dissociates) more easily as you increase the acidity (decrease the pH)   e. all the options are correct   2. Air convection in mammals is driven by a smaller pressure gradient than blood convection because:   a. Bronchioles have a greater resistance to flow than arterioles   b. bronchioles tend to have a smaller radius than arterioles and capillaries   c. air is easier to move with pressure gradients than blood    d. air generally travels farther in your body than does blood   e. air is heavier than blood 3. The rate of diffusion of gases is NOT determined by which of the following?   a. The area of the surface across which diffusion is occurring    b. The mechanical energy…

Which of the following statements is true for Bohr effect:       a.   Bohr effect describes carbon monoxide poisoning.     b.   Bohr effect prevents oxygen binding to hemoglobin.     c.   Bohr effect allows effective oxygen discharge in tissues due to higher acidity (decreased pH) than in lungs.      d. Bohr effect allows effective oxygen discharge in tissues due to lower acidity (increased pH) than in lungs.