Biochemistry
Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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Which of the following statements about 2,3-bisphosphoglycerate (2,3-BPG) are
true?
2,3-BPG lowers the affinity of myoglobin for oxygen.
2,3-BPG stabilizes the T-state of hemoglobin.
2,3-BPG has a lower affinity for HbF than for HbA.
2,3-BPG lowers the affinity of hemoglobin for oxygen.
2,3-BPG is present at about 5 mM in the blood plasma.
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Transcribed Image Text:Which of the following statements about 2,3-bisphosphoglycerate (2,3-BPG) are true? 2,3-BPG lowers the affinity of myoglobin for oxygen. 2,3-BPG stabilizes the T-state of hemoglobin. 2,3-BPG has a lower affinity for HbF than for HbA. 2,3-BPG lowers the affinity of hemoglobin for oxygen. 2,3-BPG is present at about 5 mM in the blood plasma.
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Step 1: Introduction

A three-carbon chemical compound called 2,3-bisphosphoglycerate (2,3-BPG) is involved in the metabolism of red blood cells and the glycolytic pathway. It is essential for controlling how oxygen binds to haemoglobin in red blood cells. 2,3-BPG binds to haemoglobin and aids in its release, increasing the amount of oxygen that is available to cells in tissues.

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