Which reaction intermediate (A or B) is more likely to form in the epoxide ring opening reaction? Reactions prefer to react through lower energy intermediates. Hint: how might you justify one structure being lower in energy than the other? Draw structures as part of your explanation why. F BOH F F :0₁ Br- Br Br Which alcohol structure shown below would be less acidic? Explain why. H epoxide ring opening H Structure A Dön Structure B :0. : OH

Organic Chemistry
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ISBN:9781305080485
Author:John E. McMurry
Publisher:John E. McMurry
Chapter22: Carbonyl Alpha-substitution Reactions
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Problem 64AP: The key step in a reported laboratory synthesis of sativene, a hydrocarbon isolated from the mold...
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Which reaction intermediate (A or B) is more likely to form in the epoxide ring opening
reaction? Reactions prefer to react through lower energy intermediates. Hint: how might you
justify one structure being lower in energy than the other? Draw structures as part of your
explanation why.
F
F.
BOH
F
:0.
Br
Br
Br
H
H
epoxide
ring opening
Structure A
Which alcohol structure shown below would be less acidic? Explain why.
OH
Structure B
: 0.
: OH
Transcribed Image Text:Which reaction intermediate (A or B) is more likely to form in the epoxide ring opening reaction? Reactions prefer to react through lower energy intermediates. Hint: how might you justify one structure being lower in energy than the other? Draw structures as part of your explanation why. F F. BOH F :0. Br Br Br H H epoxide ring opening Structure A Which alcohol structure shown below would be less acidic? Explain why. OH Structure B : 0. : OH
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