Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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Which primers are specific for UCP1 gene that locates in human mitpchondria?

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Step 1

What are primers?

 Primers are oligonucleotides chains consisting of 10 to 60 base pairs utilized by all living organisms in the initiation of DNA replication.

Step 2

What is UCP1 gene?

UCP1 gene encodes for mitochondrial uncoupling proteins and belongs to a gene family which is involved in the synthesis of Mitochondrila Anion Carrier Protein (MACP). Uncoupling proteins seperate the process of oxidative phosphorylation and ATP synthesis with energy emitted as heat.

Function of UCP1 gene

The uncoupling proteins encoded by this gene is responsible for mitochondrial proton leak, i.e., protons are transferred from the outer membrane to the inner membrane of the mitochondria and the anions are transferred from the inner membrane to the outer membrane of the mitochondria. They are involved in what is known as thermogenic respiration of the mitochondria, a special feature of brown adipose tissue, which emits heat (non-shivering thermogenesis).

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