Which one of the these primary protein structures is most likely to form an alpha helix that would would cross a plasma membrane from the extracellular side to the cytoplasmic side? The N terminus is outside the cell and the C terminus is inside the cell in this example. Use the diagram provided to decode the one letter amino acid abbreviations.

Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Lauralee Sherwood
Chapter2: Cell Physiology
Section: Chapter Questions
Problem 11RE
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Which one of the these primary protein structures is most likely to form an alpha helix that would
would cross a plasma membrane from the extracellular side to the cytoplasmic side? The N
terminus is outside the cell and the C terminus is inside the cell in this example. Use the diagram
provided to decode the one letter amino acid abbreviations.
Nonpolar
side chains
No charged
or electro-
negative
atoms to form
hydrogen
bonds; not
soluble in
water
Polar side
chains
Partial charges
can form
hydrogen
bonds; soluble
in water
Electrically
charged
side chains
Charged side
chains form
hydrogen
bonds; highly
soluble in
water
H
H₂N-C-C
H₂N-C-
H₂N+
Glycine (G)
Gly
H
H
H₂N*
Methionine (M)
Met
C
8*CH₂
6 OH
2011 Pearson Education, Inc.
CH₂
CH₂
S
CH₂
=0
Serine (S)
Ser
c=0
O
O
Aspartate (D)
Asp
20
H₂N-C- с
CH₂
H₂N*
HO
Acidic
Alanine (A)
Ala
H
L
CH
C
H₂N-C C
CH₂
CH₂
Threonine (T
Thr
H₂N C
Phenylalanine (F)
Phe
O
0=0
CH₂
CH₂
Glutamate (E)
Glu
ON-DTNLRRSIAGLLIRHKKE - COOH
H₂N+
ON-DTNLVLLIAGLLIRHKKE-COOH
ON-DTNLVLLRAGLLIRHKKE - COOH
H
H₂N-C-
CH₂
SH
H₂C
C
Cysteine (C)
Cys
H
0
H₂N
CH
C
Valine (V)
Val
CH₂
H₂N*
O
O
H₂N+
H
C C
CH₂
CH₂
CH₂
CH₂
NH₂
Lysine (K)
Lys
Tyrosine (Y)
Tyr
C
CH₂
OH
20
H₂N-C C
H
Tryptophan (W)
Trp
C
CH₂
O
H₂C CH₂
Leucine (L)
Leu
NH
H
CH₂
CH
H₂N
H₂N-
H
H₂N-C-C
Basic
H
O
O
CH₂
C
Asparagine (N)
Asn
CH₂
CH₂
CH₂
NH
=0
Arginine (R)
Arg
O
010
10
CNH,
NH₂
H₂N* C-
H₂CCH
Isoleucine (1)
lle
CH₂
CH₂
H
H₂N* -C-
с
H₂C
CH₂
CH₂
H₂N
Proline (P)
Pro
H₂N-C-
H
H₂N-C
-C-C
CH₂
CH₂
C
C
CH₂
Glutamine (Q)
Gin
=0
C
NH
=0
NH
Histidine (H)
His
O
o
=0
O
Transcribed Image Text:Which one of the these primary protein structures is most likely to form an alpha helix that would would cross a plasma membrane from the extracellular side to the cytoplasmic side? The N terminus is outside the cell and the C terminus is inside the cell in this example. Use the diagram provided to decode the one letter amino acid abbreviations. Nonpolar side chains No charged or electro- negative atoms to form hydrogen bonds; not soluble in water Polar side chains Partial charges can form hydrogen bonds; soluble in water Electrically charged side chains Charged side chains form hydrogen bonds; highly soluble in water H H₂N-C-C H₂N-C- H₂N+ Glycine (G) Gly H H H₂N* Methionine (M) Met C 8*CH₂ 6 OH 2011 Pearson Education, Inc. CH₂ CH₂ S CH₂ =0 Serine (S) Ser c=0 O O Aspartate (D) Asp 20 H₂N-C- с CH₂ H₂N* HO Acidic Alanine (A) Ala H L CH C H₂N-C C CH₂ CH₂ Threonine (T Thr H₂N C Phenylalanine (F) Phe O 0=0 CH₂ CH₂ Glutamate (E) Glu ON-DTNLRRSIAGLLIRHKKE - COOH H₂N+ ON-DTNLVLLIAGLLIRHKKE-COOH ON-DTNLVLLRAGLLIRHKKE - COOH H H₂N-C- CH₂ SH H₂C C Cysteine (C) Cys H 0 H₂N CH C Valine (V) Val CH₂ H₂N* O O H₂N+ H C C CH₂ CH₂ CH₂ CH₂ NH₂ Lysine (K) Lys Tyrosine (Y) Tyr C CH₂ OH 20 H₂N-C C H Tryptophan (W) Trp C CH₂ O H₂C CH₂ Leucine (L) Leu NH H CH₂ CH H₂N H₂N- H H₂N-C-C Basic H O O CH₂ C Asparagine (N) Asn CH₂ CH₂ CH₂ NH =0 Arginine (R) Arg O 010 10 CNH, NH₂ H₂N* C- H₂CCH Isoleucine (1) lle CH₂ CH₂ H H₂N* -C- с H₂C CH₂ CH₂ H₂N Proline (P) Pro H₂N-C- H H₂N-C -C-C CH₂ CH₂ C C CH₂ Glutamine (Q) Gin =0 C NH =0 NH Histidine (H) His O o =0 O
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