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Which of the following would be used by a cell to signal cells close by?
You can choose multiple answers
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paracrine |
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hormonal |
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synapse |
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direct |
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Solved in 2 steps
- You are investigating the effects of a newly discovered cell type. You have an intact synapse (including pre- and post-synaptic neurons) in a dish and observe what happens upon electrical stimulation. Following electrical stimulation of the pre-synaptic neuron, you record an action potential in the pre-synaptic neuron and an EPSP in the post-synaptic neuron. The synapse most likely utilizes which of the following neurotransmitters? Sodium (Na++) GABA Calcium (Ca++) GlutamateWhich of the following describes temporal summation? Two pre-synaptic cells send alternating signals to depolarize and then hyperpolarize. Two pre-synaptic cells send simultaneous signals to hyperpolarize. One pre-synaptic cell sends a signal to depolarize and another cell simultaneously sends a signal to hyperpolarize. One presynaptic cell sends a repeated signal to depolarize. Two pre-synaptic cells send simultaneous signals to depolarize.Which statement is TRUE about the synapse? Neurotransmitters shuttle the signal back and forth between the pre- and post-synaptic cell. The pre-synaptic cell and post-synaptic cell are in direct contact, allowing the electrical signal to seamlessly flow from one to the other. The action potential jumps from the pre-synaptic cell into the post-synaptic cell. The action potential ends in the pre-synaptic cell and neurotransmitters carry the signal across the synaptic cleft to the post-synaptic cell.
- Which of the following are the likely explanations for the failure of a postsynaptic neuron to trigger an action potential? Select all that apply. The EPSPs are neutralized by the neurotransmitter The summation of IPSPs and EPSPs is insufficient to depolarize the cell to threshold The synapses generating the EPSPs are too close to the axon hillock The synapses generating the EPSPs are too far from the axon hillockOrder the following events that occur during a nerve impulse. a few milliseconds behind the Na channels, K channels open and allow K into the cell (-70 mV) Na voltage-gated channel opens and Na leaves the cell (-55 mV) some stimulus is detected (-70 mV) more Na outside the cell causes other nearby Na channels to open (+35 mV) the cell rebalances the Na and K ions in preparation for the next impulse (~3-4ms)Place the following events in chronological order from 1-8: Nat enters the cell, and depolarization occurs to approximately +30 mV. The voltage across the cell membrane is -70 mV, the resting membrane potential. Upon reaching the peak of the action potential, the VG Nat channels are inactivated by the closing of their inactivation gate and the activation gate of each VG K channel opens. VG K channels close by the closing of their activation gate, and the resting membrane potential is gradually restored. An excitatory post-synaptic potential depolarizes the membrane to threshold and the activation gate of VG Nat channels open. Upon returning to the resting membrane potential, VG Na channels are reset by opening of the inactivation gate and the closing of the activation gate. VG K+ channels are slow to close, resulting in an excess of K* efflux and hyperpolarization. Depolarization occurs as K+ flows out of the cell.
- A post-synaptic cell receives a signal that causes it to hyperpolarize. Which of the following gates must have been opened to cause this? Na+ O K+ Any of the above Ca2+Parkinson's Disease Parkinson's disease is neurodegenerative disorder that affects movement. Most people affected with Parkinson's disease demonstrate rigidity, slow movement, and shaking. The symptoms of Parkinson's disease occur when the cells that produce dopamine neurotransmitters die in the brain. Explain how the signal transmission at a synapse in an individual with Parkinson's disease is different than an unaffected individual. Describe the normal process of signal transmission at a synapse. Start with the arrival of an action potential at the axon terminal and include the name of the neurotransmitter that is affected by Parkinson's disease. Explain how the process is different in individuals affected with Parkinson's disease.Which of the following changes would increase serotonin (5-HT) signaling between neurons? Select all that apply; partial point deduction for incorrect choices. O increase in serotonin synthesis O increase in the number of facilitating interneurons O decrease of serotonin receptors in the post-synaptic neuron inhibition of serotonin reuptake transporters O increase in activity of serotonin reuptake transporters O faulty transport and docking of synaptic vesicles decrease in serotonin synthesis O increase of serotonin receptors in the post-synaptic neuron
- repeatedly stimulated, and recordings are made of the response. What effect would you expect to observe? Hint: think 3) What response would you predict in a post-synaptic cell in the above situation? Follow directions and answer the following questions: A drug that blocks ATPase enzymes (enzymes that hydrolyze ATP) is introduced into a neuron. The neuron is then 1) What is the effect of AP frequency on the amount of transmitter released at the terminal? Activity 8: Synaptic Transmission at Axon Termines Apply Your Knowledge of the role of the Na+/K+ ATPase in the physiology of a neuron.Choose all that apply [Na*] + [K'] | + + + + This diagram is a drawing of normal conditions that occur in a neuron's axon (not all details are included). This stage that a living neuron would be in, would show that no positive ions are inside the cell current is traveling down the axon the cell will be at rest once the Na ions enter the cell the cell is at rest Na ions are predominantly outside the celStarting from the cell body of the pre-synaptic neuron what is the correct order of structures involved in neuronal communication? Put the items in the correct order from presynaptic to postsynaptic neuron.