Which of the following are the likely explanations for the failure of a postsynaptic neuron to trigger an action potential? Select all that apply. The EPSPs are neutralized by the neurotransmitter The summation of IPSPs and EPSPS is insufficient to depolarize the cell to threshold The synapses generating the EPSPs are too close to the axon hillock The synapses generating the EPSPs are too far from the axon hillock 0000
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- Assume presynaptic excitatory neuron A terminates on a postsynaptic cell near the axon hillock and presynaptic excitatory neuron B terminates on the same postsynaptic cell on a dendrite located on the side of the cell body opposite the axon hillock. Explain why rapid firing of presynaptic neuron A could bring the postsynaptic neuron to threshold through temporal summation, thus initiating an action potential, whereas firing of presynaptic neuron B at the same frequency and the same magnitude of EPSPs may not bring the postsynaptic neuron to threshold.View the University of Michigan Webscope (http://openstaxcollege.org/l/nervefiber) to see an electron micrograph of a cross-section of a myelinated nerve fiber. The axon contains microtubules and neurofilaments, bounded by a plasma membrane known as the axolemma. Outside the plasma membrane of the axon is the myelin sheath, which is composed of the tightly wrapped plasma membrane of a Schwann cell. What aspects of the cells in this image react with the stain that makes them the deep, dark, black color, such as the multiple layers that are the myelin sheath?Which of the following combinations of spatial summation of postsynaptic potentials (PSP) would result in an action potential in a typical neuron? The voltage given for each PSP is measured as it reaches the axon hillock. Axon A EPSP 25 mV & axon B IPSP 10 mV Axon A IPSP 25 mV & axon B EPSP 10 mV Axon A IPSP 5 mV & axon B IPSP 5 mV Axon A EPSP 5 mV & axon B EPSP 5 mV
- If action potential propagation from one neuron to another neuron requires ACh release, what event at the synaptic cleft explains the need for action potentials to arrive at a high rate before the post-synaptic membrane achieves threshold? the lack of sodium voltage gated channels on the post-synaptic membrane O the rapid breakdown of ACh by ACHE at the synaptic cleft the slow release of ACh by the synaptic vessicles the slow movement of sodium through chemical gates Previous Next MacBook AirSynaptic transmission depends upon :- a-direct transmission of impulses from the presynaptic neuron to the postsynaptic neuronb- diffusion of neurotransmitters from synaptic knobs into the soma and dendrites of postsynaptic neuronsc- presence of voltage-gated Ca ++ channels in membrane of synaptic knobsd- presence of voltage-gated Ca ++ channels in the subsynaptic membraneIf a post synaptic neuron is stimulated to threshold by spatial summation this implies that the post synaptic cell has a lower than normal threshold the postsynaptic cell has many synapses with many presynaptic neurons the post synaptic cell is getting stimulated many times during a short period of time by a single presynaptic neuron the post synaptic cell is slow to repolarize
- A neuron has a resting membrane potential of -70 milivolts (mV) and a threshold value of -55 mV. Three synapses on the body of this neuron receive the impulses listed below. hyperpolarisation by 5 mV • depolarisation by 15 mV • depolarisation by 10 mV ENTER THE MEMBRANE POTENTIAL AS A NUMBER WITH + OR - IN FRONT OF IT. The final membrane potential will be mV and this cause an action potential becasue it is v than theIn terms of function when a presynaptic neuron receiving input from a nearby inhibitory neuron, it can be inferred that the both neurons firing won't be synchronized activation of the inhibitory neuron is nullified activation of the presynaptic neurotransmitter release is enhanced this type of interaction represents a regulatory input of neuronal activationWhich of the following statements is TRUE about the depolarization phase of action potential? Group of answer choices: Na-K pump initiates depolarization. Potassium ion channels quickly opens to allow efflux of ions. Depolarization is characterized by the movement of calcium ions out of the cell. Depolarization is primarily triggered by opening of sodium ion channels asap pls
- If a neuron is stimulated simultaneously by 2 stimuli at its dendrites (one generates a very large hyperpolarizing potential and the other generates a very small depolarizing potential). What would happen to this neuron? Group of answer choices The summation of these two graded potentials will generate an action potential and this action potential will travel down the axon. Summation of these two graded potentials will cause the membrane potential at the axon hillock to be more negative. These graded potentials will bring the resting membrane potential to 0 mV. These graded potentials with opposite polarity would therefore generate two action potentials and they will travel along this neuron in opposite direction.Place the following actions of synaptic transmission in the correct order: 1. voltage-gated Ca+2 synaptic terminal of presynaptic cell channels open on 2. voltage-gated Nat channels open on axon of presynaptic cell 3. neurotransmitter released via exоcytosis 4. chemical-gated channels open on post- synaptic cell A 1, 2, 3, 4 В 2, 3, 4, 1 C 2, 1, 3, 4 D 4, 2, 1, 3 3, 4, 2, 1 6.Based upon the changes in permeability seen in the trace below and your knowledge of ion distributions across a cell, predict how ion movements would change during an action potential. Drag and drop each phrase into the appropriate box on the action potential trace. Drag the appropriate labels to their respective targets. Note: not all labels will be used. ►View Available Hint(s) Sodium (Na+) ions move to the axon Sodium (Na) ions move out of the axon Less potassium (K) ions move out of the axon Potassium (K) ions move out of the axon Potassium (K¹) ions move into the axon Sodium (Na) ions stop moving in Membrane potential (mv) +30 +10 0 -10- -30 -50 -70 -90 A PNa 0 PNa 5 6 1 PK Threshold PK 2 Reset Help