Which of the following statements related to intercellular junctions is false? Cadherins are important cell-cell adhesion proteins. A cadherin-mediated junction involves many cadherin molecules to achieve strong adhesion. The cytoplasmic domain of cadherins interacts with actin or intermediate filament cytoskeleton through adaptor proteins. Because tight junctions seal the membrane of adjacent epithelial cells, transmembrane proteins in the apical portion of the plasma membrane cannot move to the basal lateral domain or vice versa. Proteins can diffuse through an open gap junction.

Which of the following statements related to intercellular junctions is false? Cadherins are important cell-cell adhesion proteins. A cadherin-mediated junction involves many cadherin molecules to achieve strong adhesion. The cytoplasmic domain of cadherins interacts with actin or intermediate filament cytoskeleton through adaptor proteins. Because tight junctions seal the membrane of adjacent epithelial cells, transmembrane proteins in the apical portion of the plasma membrane cannot move to the basal lateral domain or vice versa. Proteins can diffuse through an open gap junction.

Human Physiology: From Cells to Systems (MindTap Course List)

9th Edition

ISBN:9781285866932

Author:Lauralee Sherwood

Publisher:Lauralee Sherwood

Chapter3: The Plasma Membrane And Membrane Potential

Section: Chapter Questions

Problem 7RE

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In the fluid mosaic model: plasma membrane proteins orient their hydrophilic sides toward the internal bilayer. phospholipids often flip-flop between the inner and outer layers. the mosaic refers to proteins attached to the underlying cytoskeleton. the fluid refers to the phospholipid bilayer. the mosaic refers to the symmetry of the internal membrane proteins and sterols.
Intermediate filaments (IFs) function to provide mechanical strength to the cell and for internal organization of the cells. The intermediate filament _______________ plays a key role in connecting epithelial cells to the extracellular matrix. The IF binding protein________ plays key role in connecting the IFs in the nucleus with the cytoskeleton in the cytoplasm to help position the nucleus. keratin, SUN-domain protein SUN-domain proteins, lamin lamin, keratin SUN-domain proteins, keratin lamin, SUN-domain protein keratin, lamin
Match the following to their proper description (answers may be used more than once). Gap junctions Adhering junctions Desmosomes Hemidesmosomes Tight junctions Tight junctions Tight junctions Connexons Connexons Zonulae adherens Cadherins Desmosomes Are also known as “zonulae adherens”. Are also known as “zonulae occludens”. Are calcium ion-dependent glycoproteins that mediate adhesion in adhering junctions. Are hexameric complexes formed by connexin proteins. Bind the cells to the basal lamina. Contain a central hydrophilic pore and occur in gap junctions. Contain protein filaments. Encircle the cell and provide firm connections with neighboring cells. Form seals that prevent the flow materials between adjacent epithelial cells. Form thin bands that completely encircle the cell. Permit the rapid exchange of materials between adjacent cells. Provide firm adhesion between cells via protein filaments that are coupled to intracellular filaments via a protein plaques.
"Tight junctions perform two distinct functions: they seal the space between cells to restrict paracellular flow and they fence off plasma membrane domains to prevent the mixing of apical and basolateral membrane proteins" is true or false.
Most cells are linked together forming a tissue and membrane junctions are important factors in this phenomenon. Compare and contrast the structure and function of a tight junction versus a desmosome versus a gap junction.
Which of the following most accurately describes tight junctions? They allow adjacent cells to share tensile stress by linking their intermediate filament cytoskeletons They allow adjacant cells to control the passage of molecules between them They bind actin filaments and assist cells to crawl They allow cells to directly exchange small molecules with adjacent cells
Which of the following cell junctions are involved with anchoring of the cell to the extracellular matrix? Select all that apply Desmosomes Gap Junctions Hemidesmosomes Adherens junctions
Would substances be able to pass through the plasma membrane if the phospholipid tails of the plasma membrane were both saturated fatty acids? No, saturated fatty acids would cause the plasma membrane to loss the fluidity it has by having some unsaturated fatty acids present. No, saturated fatty acids would cause the plasma membrane to be more fluid. Yes, saturated fatty acids would cause the plasma membrane to be a solid versus liquid. Answer not listed.
Many diseases are characterized by fibrosis, which is excess scarring. This scarring is often caused by too much collagen accumulating in the extracellular matrix. Which of the following strategies is MOST likely to work for preventing fibrosis? O Altering the endomembrane system to increase collagen secretion. O Altering the endomembrane system to decrease detection of the internal start transfer sequence of collagen. O Altering the endomembrane system to increase collagen endocytosis. Altering the nuclear export of collagen via lamins, followed by kinesin-mediated exocytosis.
In vertebrates, which cell-cell junction allows for direct chemical communication between adjacent cell cytoplasms, without contact with the extracellular fluid, and is composed of the transmembrane protein connexin? O Desmosome O Gap junctions O Adherens junctions O Tight junctions O Focal adhesions
Which of the following is true regarding the permeability of the cytoplasmic membrane? Nothing can diffuse across the membrane All molecules can freely diffuse across it Only non-polar molecules can diffuse across the membrane It is generally impermeable to ions, polar molecules
Crossing a cell membrane by simple diffusion can be distinguished from facilitated diffusion by which of the following: Select all that apply. Simple diffusion moves molecules down a concentration gradient while facilitated diffusion moves molecules up a concentration gradient Simple diffusion does not require membrane proteins; facilitated diffusion requires specific membrane proteins Simple diffusion does not require energy; facilitated diffusion requires energy Simple diffusion is not saturable; facilitated diffusion rates are limited by the number of functional membrane proteins and can be saturated