Which of the following statements is false about DNA replication? A) Each lagging strand of DNA is started by an RNA primer. B) DNA polymerase joins nucleotides in the 5' to 3' direction only. C) The leading strand of DNA is made continuously. D) More than one replication fork is present. E) A replication bubble opens in one direction only.

From which end of a strand of nucleic acid does DNA polymerase I REMOVE nucleotides? A) 5' B) 3' C) 2' D) N-term E) C-term

You discover an E. coli mutant that has a non-functional DNA polymerase III. Such a bactèria; a) Would not be able to synthesize new strands of DNA b) Would not be able synthesize the leading strand of DNA Oc) Would produce new strands of DNA still containing short RNA primers Od) Would be able to synthesize the lagging strand of DNA only

For double-stranded DNA, which of the following statements is true? a) A = C b) A = G and C = T c) A + C = G + T d) A + T = G + C e) B and C are true

The E. coli chromosome is 1.28 mm long. Under optimal conditions, thechromosome is replicated in 40 minutes.(a) What is the distance traversed by one replication fork in 1 minute?(b) If replicating DNA is in the B form (10.4 base pairs per turn), how manynucleotides are incorporated in 1 minute in one replication fork?(c) If cultured human cells (such as HeLa cells) replicate 1.2 m of DNAduring a five-hour S phase and at a rate of fork movement one-tenthof that seen in E. coli, how many origins of replication must the cellscontain?(d) What is the average distance, in kilobase pairs, between these origins?

Compare the process of Replication, Transcription, and Translation by describing the following properties for each: (circle, highlight, bold or whatever mechanism you want to use to indicate your answer)

Double-stranded breaks are repaired by     a)  homologous recombinational repair.   b)  translesion repair.   c)  direct reversal of DNA damage

Replication slippage can cause indels in repetitive regions of DNA. Which of the following statements is not true?a) slippage of the new daughter strand causes repeat expansionb) slippage of the template strand causes repeat deletion c) slippage can cause indels on either the daughter or the template strandd) the indel mutation becomes fixed in one daughter cell's genome only after the next round of replication e) none of the above (all are true statements)

During DNA replication the bond between the growing strand and the incoming nucleotide is formed between the phosphate group of the nucleotide being added and the of the last nucleotide in the polymer. a) a nitrogen from the nitrogen containing base b) the fifth carbon c) the 5' phosphate d) the 3' OH

When a cell is to divide, its DNA must be replicated (copied). a) Indicate the main participating components and their functions. b) Why is it important that the replication goes right and that relatively few mutations occur during the replication?