Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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Question
Which of the following is true?
a. |
Enhancers are proteins that bind to activator DNA sequences.
|
|
b. |
Activators are proteins that bind to insulator sequences
|
|
c. |
Repressors are proteins that bind to enhancer DNA sequences. |
|
d. |
Repressors are proteins which bind to silencer DNA sequencers.
|
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- Match whether the protein binds directly or indirectly (assuming it does) to DNA and whether to the enhancer or promoter. Items may be matched to multiple choices and not all choices will be used. 1. Directly to enhancer Repressors 2. Directly to promoter Activators 3. Indirectly to enhancer TBP associated factors 4. Indirectly to promoter >arrow_forwardWhich of the following is NOT true of DNA Methylation. A. DNA methylation is typically correlated to gene repression. B. On a given gene, histone modifications or DNA methylation could be used, but not both at the same gene. C. DNA methylation can be used in mismatch repair to identify the parent strand after DNA replication. D. DNA methylation typically occurs on dCTP nucleotides in eukaryotes. E. DNA methylation can be inherited through mitosis.arrow_forwardEnhancers: a. are always located upstream of the TATA sequence b. are always within 200 bp of the TATA sequence c. are responsible for time and tissue specific transcription d. All the above are true.arrow_forward
- A repressor is a __________ that _________ transcription. a. small effector molecule, inhibits b. small effector molecule, enhances c. regulatory protein, inhibits d. regulatory protein, enhancesarrow_forwardBinding of______ to_______ in DNA can increase the rate of transcription of specific genes. a. activators; repressors b. activators; enhancers c. repressors; operators d.repressors; enhancerarrow_forwardIntitial analysis of a human colon cancer tumor indicates mutations/defects in APC, B-Raf and p53. Which of the genes below is also most likely mutated in this tumor (select one)? A. Beta-catenin B. K-RAS C. SMAD4 D. MDM2 E. p14 ARFarrow_forward
- Which of the following statements about the lac operon is correct? 1. lacZ, lacY and lacA proteins are translated using the same RNA molecule. 2. Lacl is a gene that codes for allolactose. 3. Allolactose activates transcription of lacz, lacY and lacA. 4. In the presence of lactose, the repressor is active. A. 1, 2 and 3 B. 1 and 3 C. 2 and 4 D. 4 only E. All of 1, 2, 3, and 4 are correct.arrow_forwardYou identify a fragment of DNA that, when fused to a GFP reporter, can express GFP in a mouse's eyes. You suspect some piece of that fragment represents a promoter and another piece represents an enhancer. You want to know which is which. What experiments do you perform to see which piece is a promoter and which is an enhancer? Hint: remember the important differences between promoters and enhancers. Then build constructs that test those differences.arrow_forwardWhich of the following is false regarding the role of mediator complex in eukaryotic transcription initiation? a. Mediator complex interacts with RNA pol II b. Mediator binds to upstream enhancer sequences c. Mediator interacts with general transcription factors d. Mediator interacts with transcriptional activators e. All of the above are true about the mediator complexarrow_forward
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