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A:
Assembly of transcription initiation complexes is mainly controlled by?
Promotors
Activators
Repressors
Suppressors
B & C
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- Explain the different events under post transcriptional modification. A. 5'capping B. Polyadenylation C. RNA splicingWhat is one function of TFIIH during transcription? a. Recruiting the TATA-box binding protein to the TATA-box. b. Terminating transcription via factor-dependent termination. c. Capping the 5' end of mRNA with 7-methylguanylate. d. Phosphorylating the CTD of RNA polymerase.How is transcription directly controlled in eukaryotic cells? a. through the use of phosphorylation b. by means of apoptosis c. using transcription factors and activators d. when chromatin is packed to keep genes turned on e. None of these are correct.
- Which of these BEST DESCRIBE tryptophan in the Trp Operon? A. Acts as a corepressor B. Acts as a coactivator C. Acts as an inducer D. Acts as an enhancerWhat is the central component of a transcription initiation complex? a. DNA polymerase b. RNA polymerase c. DNA d. RNA e. RNAiCan one transcription factor sometimes act as a repressor and sometimes act as an activator? a. Yes, but it depends on where the transcription factor binds in the promoter b. Yes, but it depends on other proteins that might act with the transcription factor c. No, transcription factors are always either activators or repressors d. Yes, but only if a mutation happens
- Promoters are DNA sequences a. near a transcription start site b. bound to a repressor protein c. that inhibit transcription of a gene d. that stimulate ncRNA activityWhich statement/s is/are TRUE about transcription?A. During transcription, DNA polymerase binds to RNA and separates the DNA strands.B. RNA polymerase uses one strand of DNA as a template to assemble nucleotides into a strand of RNA.C. RNA polymerase binds only to DNA promoters, which have specific base sequences.D. Promoters are signals in RNA that indicate to RNA polymerase where to begin transcription.E. Transcription occurs in the 3’ to 5’ direction with respect to the growing mRNA strand.To which part of DNA do the eukaryotic transcription factors bind? a. promoter regions enhancers O b. O C. AUG (the first codon) O d. operator Oe. DNA introns
- What will result from the binding of a transcription factor to an enhancer region? a. decreased transcription of an adjacent gene b. increased transcription of a distant gene c. alteration of the translation of an adjacent gene d. initiation of the recruitment of RNA polymeraseAfter treating cells in tissue culture with an HDAC inhibitor, which of the following is the most likely outcome? A. Repression of transcription B. Promoter methylation C. Enhanced splicing D. Activation of transcription E. Depends on the cell typeWhat would happen if a lysine residue that was normally acetylated was mutated to an arginine? A. There would probably be no affect on transcription B. The nucleosome affected by this mutation would be more likely to be uncondensed C. Genes within or near the nucleosome affected by this mutation would be more likely to be repressed D. RNA Pol II would have an easier time accessing the DNA at or near the affected nucleosome E. B and C are both correct