Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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Which of the following is a likely outcome of Rifampin treatment?
Transcriptional elongation is blocked
Peptidyltransferase activity is inhibited at the ribosome
The peptidoglycan cell wall is degraded by peptidoglycan hydrolases
Double stranded DNA breaks
Pore formation in the outer membrane
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Transcribed Image Text:Which of the following is a likely outcome of Rifampin treatment? Transcriptional elongation is blocked Peptidyltransferase activity is inhibited at the ribosome The peptidoglycan cell wall is degraded by peptidoglycan hydrolases Double stranded DNA breaks Pore formation in the outer membrane
Sigma factors are essential for bacterial survival. Why?
They are required for initiation of transcription -without sigma factors, nothing would get transcribed.
They are important to control which genes are transcribed when - without them, all genes would be transcribed
all the time, which would waste energy.
They are required to contend with the supercoiling that occurs during transcription - without them, RNAP would
be halted by the supercoils.
They are required for RNA Polymerase to be able to terminate a transcript - without them, RNAP would just keep
transcribing huge, long transcripts
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Transcribed Image Text:Sigma factors are essential for bacterial survival. Why? They are required for initiation of transcription -without sigma factors, nothing would get transcribed. They are important to control which genes are transcribed when - without them, all genes would be transcribed all the time, which would waste energy. They are required to contend with the supercoiling that occurs during transcription - without them, RNAP would be halted by the supercoils. They are required for RNA Polymerase to be able to terminate a transcript - without them, RNAP would just keep transcribing huge, long transcripts
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